Oligonucleotide definition

Oligonucleotide means a synthetic compound that comprises or consists of at least 5 linked nucleosides (including any analog, variant, mimic, or mimetic thereof). For clarity, the [***] of Oligonucleotides [***]. Oligonucleotides [***]. Oligonucleotides may be single-stranded or multi-stranded.
Oligonucleotide means a [ * ] non-protein, non-peptide encoding nucleic acid molecule including those with [ * ] used as a human therapeutic and/or prophylactic compound comprising between [ * ] including oligonucleotide analogs which may include natural or non-natural heterocycles, sugars and/or backbone linkage modifications, capable of specifically inhibiting the function, activity or expression of a gene. For the purposes hereof Oligonucleotide (a) shall include [ * ], and (b) shall exclude polymers in which the linkages are [ ]
Oligonucleotide means [***].

Examples of Oligonucleotide in a sentence

  • Recombinant DNA technology and drug discovery rDNA technology, hybridoma technology, New pharmaceuticals derived from biotechnology; Oligonucleotide therapy.

  • Oligonucleotide primers are generally 20–40 nucleotides in length and ideally have a GC content of 40–60%.

  • Oligonucleotide antiviral therapeutics: antisense and RNA interference for highly pathogenic RNA viruses.

  • Oligonucleotide microarray analysis of genomic imbalance in children with mental retardation.

  • The price per Nucleic Acid Molecule, however, shall not exceed [*] of the Oligonucleotide Market Price.


More Definitions of Oligonucleotide

Oligonucleotide means a short single-stranded nucleic-acid product comprised of at least six linked natural or chemically-modified nucleosides.
Oligonucleotide means any single stranded, [ * ] oligonucleotide including those [ * ] used as a human therapeutic and/or prophylactic compound containing between [ * ] nucleotides and/or nucleosides including oligonucleotide analogs which may include [ * ]. For purposes of this agreement, Oligonucleotide shall specifically exclude oligonucleotides used in gene therapy except [ * ] an oligonucleotide, oligonucleotides used as [ * ] or oligonucleotides used as adjuvants. Oligonucleotide shall also specifically exclude polymers in which the linkages are amide based, such as peptides and proteins and shall also exclude [ * ].
Oligonucleotide means a synthetic oligonucleotide without an [*] attached. A Purified Oligonucleotide will have a purity of at least [*]%. However, the value of the required purity of a Oligonucleotide may be amended pursuant to Section 10.06 of the Agreement.
Oligonucleotide means ( * )
Oligonucleotide means any compound containing between [* ] nucleotides and/or nucleosides, including oligonucleotide analogs which may include natural or modified heterocycles, sugars and or backbone linkages.
Oligonucleotide means an oligomer or polymer made up of at least six nucleosides or nucleotides. Oligonucleotide includes RNA or DNA fragments. Oligonucleotides also include mimetics of RNA or DNA that are composed of naturally occurring and/or non-naturally occurring bases. In addition, an oligonucleotide may include modified and/or non-naturally occurring sugars and/or intersugar linkages or the sugars may be partially or completely absent. Oligonucleotides include structures where adjacent nucleosides are linked together by phosphate groups and/or modified or non-natural internucleoside linkages, including, without limitation, amide linkages to form the internucleoside backbone of the oligonucleotide whether or not such linkages retain a phosphorus atom in the linkage. A nucleotide is a nucleoside that includes a phosphate group covalently linked to the sugar portion of the nucleoside.
Oligonucleotide or "Oligo" means a plurality of nucleotides or nucleotide analogs forming a nucleotide chain and conforming to the specifications and criteria set forth in Appendix A, for supply and delivery to Sequenom and Sequenom Accounts.