Mipomersen definition

Mipomersen means mipomersen sodium, formerly known as ISIS 301012.
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Mipomersen means mipomersen sodium, formerly known as ISIS 301012, including all pharmaceutically acceptable salts, solvates, hydrates, hemihydrates, metabolites, pro-drug forms, stereoisomers, enantiomers, racemates and all optically active forms thereof.
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Examples of Mipomersen in a sentence

  • Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial.

  • Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk: a randomized, double-blind, placebo-controlled trial.

  • Mipomersen, an apolipoprotein B Synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomized, double-blind, placebo-controlled trial.

  • Juxtapid™ (Lomitapide) and Kynamro® (Mipomersen) Approval Criteria:1.

  • Mipomersen (kynamro): a novel antisense oligonucleotide inhibitor for the management of homozygous familial hypercholesterolemia.

  • Juxtapid® (Lomitapide) and Kynamro® (Mipomersen) Approval Criteria:1.

  • Mipomersen active pharmaceutical ingredient is manufactured by Isis Pharmaceuticals, Inc., Carlsbad, California, USA.The Sponsor or designee will provide the Investigator with packaged study drug labeled in accordance with specific country regulatory requirements.8.2.2 Study Drug PreparationThe study drug must be brought to room temperature prior to administration.

  • This Supply Agreement will remain in effect as long as Isis and Genzyme mutually agree for Isis to supply Mipomersen API as described in the Agreement.

  • Isis will produce the bulk API for Mipomersen under cGMP conditions and in accordance with the Quality Agreement between the Parties and referencing this Supply Agreement (the “Quality Agreement”), in the amount specified in the applicable Firm Order for use for the phase II clinical trials, the Pivotal Trial(s) and the initial commercial launch of Mipomersen.

  • Raal et al., Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: A randomised, double-blind, placebo-controlled trial.

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