LEPTIN definition

LEPTIN means any cytokine-like hormone expressed primarily in white adipose tissue and encoded by the OB gene or any naturally occurring or non-naturally occurring modified version thereof.
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LEPTIN means r-metHuLeptin, the polypeptide having the amino acid sequence set forth in Exhibit A of this Agreement.
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LEPTIN means (i) the OB Polypeptide and fragments and species variants thereof; (ii) A-100 Leptin; (iii) A-200 Leptin; and (iv) any other molecule or other moiety that agonizes the natural physiological receptor for A-100 Leptin (“Leptin Receptor”), including any glycosylated or PEGylated form of (i), (ii), (iii) or (iv), as well as any analog of (i), (ii), (iii) or (iv) disclosed in any patent or patent application within Licensed Patent Rights. Leptin shall not include any pharmaceutical component which antagonizes the Leptin Receptor.
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Examples of LEPTIN in a sentence

  • Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects.

  • Leptin and hunger levels in young healthy adults after one night of sleep loss.

  • Leptin is associated with increased risk of myocardial infarction.

  • Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass.

  • Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis.

  • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression.

  • Leptin levels are dependent on sleep duration: relation- ships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin.

  • Leptin levels are dependent on sleep duration: relationships with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin.

  • The Vice-Chair of the school council shall be a council member elected each July by council members and serve for one year.

  • Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase.

Related to LEPTIN

  • haemophilia means an inheritable disease, usually affecting only male but transmitted by women to their male children, characterised by loss or impairment of the normal clotting ability of blood so that a minor would may result in fatal bleeding;

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.

  • Veterinarian means a veterinarian authorized by law to practice veterinary medicine in this State.

  • HIV means human immunodeficiency virus.

  • Biological agent shall mean any pathogenic (disease producing) micro-organism(s) and/or biologically produced toxin(s) (including genetically modified organisms and chemically synthesized toxins) which cause illness and/or death in humans, animals or plants.

  • Field means [***].