KTE-C19 definition

KTE-C19 means chimeric antigen receptor (“CAR”), transduced autologous T cells directed against the CD19 antigen for the treatment of B-cell lymphomas and leukemias, as described in the Joint Venture Contract.
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KTE-C19 means Kite’s proprietary anti-CD19 CAR-T Product known as KTE- C19 and as described in Schedule 1.57.
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Examples of KTE-C19 in a sentence

  • Phase 1 Results of ZUMA-1: A Multicenter Study of KTE-C19 Anti-CD19 CAR T Cell Therapy in Refractory Aggressive Lymphoma.

  • Axicabtagene ciloleucel (KTE-C19), an anti- CD19 CAR T therapy for the treatment of relapsed/refractory aggressive B-cell non-Hodgkin's lymphoma.

  • The ’465 Patent formed the basis for the drug KTE-C19, now known as YESCARTA®.

  • FDA approved KTE-C19 as a “CD19-directed genetically modified autologous T cell immunotherapy indicated for the treatment of adult patients with relapsed or refractory large B-cell lymphoma after two or more lines of systemic therapy.” Kite markets KTE-C19 under the name YESCARTA®.

  • In December 2014, Kite submitted to FDA its investigational new drug application (“IND”) investigating KTE-C19 in aggressive B-cell lymphomas.

  • Kite Pharma Announces Positive Topline KTE-C19 Data from ZUMA-1 Pivotal Trial in Patients with Aggressive Non-Hodgkin Lymphoma (NHL).

  • KTE-C19-101 A phase 1/2 multicenter study evaluating the safety and efficacy of KTE-C19 in subjects with refractory aggressive nonhodgkin lymphoma (ZUMA-1).

  • Characterization of anti-CD19 chimeric antigen receptor (CAR) T cell-mediated tumor microenvironment immune gene profile in a multicenter trial (ZUMA-1) with axicabtagene ciloleucel (axi-cel, KTE-C19).

  • Preliminary results of prophylactic tocilizumab after axicabtagene ciloleucel (axi-cel; KTE-C19) treatment for patients with refractory, aggres- sive non-Hodgkin lymphoma (NHL).

  • Kite Pharma Receives FDA Breakthrough Therapy Designation for KTE-C19 for the Treatment of Refractory, Aggressive Non Hodgkin Lymphoma (NHL).

Related to KTE-C19

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