Intention to treat definition

Intention to treat means a procedure in the conduct and analysis of randomized controlled trials. All patients allocated to a given arm of the treatment regimen are included in the analysis whether or not they received or completed the prescribed regimen. Failure to follow this step defeats the main purpose of random allocation and can invalidate the results.
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Intention to treat means analysing all randomised patients for the most important outcome measures, and on the most important moments of effect measurement irrespective of non-compliance and co-interventions.
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Intention to treat means that the analysis is based on the initial intentions to provide tuition, rather than whether or not pupils actually received tuition. Our analysis was not done on an ‘intention to treat’ basis: if a pupil was intended to receive tuition, but for some reason did not, they would be excluded from our analysis.
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Examples of Intention to treat in a sentence

  • Intention to treat analysis, compliance, drop-outs and how to deal with missing data in clinical research: a review.

  • Intention to treat analysis is related to methodological quality.

  • Intention to treat analysis in clinical trials when there are missing data.

  • Refractory status epilepticus in children: Intention to treat with continuous infusions of midazolam and pentobarbital.

  • Two different analysis sets are defined: (Modified) Intention to treat setThis analysis set includes all subjects where the outcome can be calculated (more than two blood samples taken), even though the subject was not observed the full 18 weeks.

  • Table 9: Universal effects - Intention to treat analysis OutcomeIntervention group n Mean(95% CI) H1: Children in classes implementing FRIENDS demonstrate measureable improvements in Key Stage 2 Maths and Reading combined scores (equal weighting) when compared to those children attending comparison classes.

  • Intention to treat analysis was used for the assessment of the disease or PFS and the comparison between various regimens was done using the Kaplan Maier curves.

  • Intention to treat (ITT) patient-survival of at least 5 years must be preferred to absolute survival for all end-stage liver disease (ESLD) patients, with or without HCC, because ITT analysis can capture the entire therapeutic process, including livertransplantation.

  • Intention to treat analysis Whilst Novartis maintains the infused population is most appropriate, acknowledging the strong views expressed by the evaluators, the resubmission adopts the ITT population in the base case analysis.

  • Intention to treat analysis suggests that 96/283 (34%) completed 24 weeks of NTX treatment as compared to 115/287 (40%) for buprenorphine (RR 0.85, 95% CI 0.68, 1.05).

Related to Intention to treat

  • Intentionally means that the person referred to has a purpose to do or fail to do the act or cause the result specified or believes that the act or failure to act, if successful, will cause that result. A person "intentionally" violates a statute:

  • Unreasonable adverse effects on the environment means any unreasonable risk to humans or the environment, taking into account the economic, social, and environmental costs and benefits of the use of any pesticide.

  • Inducement means any fee, commission, or any non-monetary benefit provided by or to such an intermediary or undertaking in connection with the distribution of an insurance-based investment product, to or by any party except the customer involved in the transaction in question or a person acting on behalf of that customer;