Epitope definition

Epitope means a molecular region of an Antigen, which is involved in recognition by a particular immunoglobulin, or in the context of T cells, by a T cell receptor and/or Major Histocompatibility Complex (MHC) receptor.
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Epitope means only Epitope, Inc., as a separate legal entity, excluding all other affiliated corporations.
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Epitope means the portion of an antigen that makes contact with a particular antibody or T cell receptor.
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Examples of Epitope in a sentence

  • Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction.

  • Ensure there is adequate alcohol, distilled or de-ionized water, BOND Dewax Solution (supplied as ready-to-use), BOND Epitope Retrieval Solution 1 (supplied as ready-to-use) and BOND Wash Solution (supplied as x10 concentrate) in the bulk reagent containers to perform the required staining runs.

  • In addition, antibody-FcR engagement has been reported to be of greater importance in treatment settings than when used as a prophylaxis (Winkler et al., 2021).‌ Epitope resilience in the face of emerging VOCs is a key concern for antibody-based antiviral agents, with both casirivi- mab (REGN10933; Regeneron) and bamlanivimab (LyCo555; Eli Lilly) reported to lose activity against B.1.351, in particular (Wang et al., 2021c).

  • Effective September 29, 2000, in connection with the merger of Epitope, Inc.

  • Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction.

  • Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction.

  • STC Technologies and Epitope were merged into our Company on September 29, 2000.

  • Epitope mapping with overlapping peptide subpools at 2.5 and 3 mo identified a positive ELISPOT response against peptide DTEEEDFHVDQVTTV (17).

  • Considering the paucity of omics-level big data sets for SARS-CoV-2 up until now, existing data hubs that contain information for other coronaviruses such as UniProt, NCBI Genome Database, The Immune Epitope Database and Analysis Resource (IEDB), and The Virus Pathogen Resource (ViPR) will serve as useful resources for computational and bioinformatics research on SARS-CoV-2.

  • S3).The Importance of HLA Restriction on the Presentation of the Immunodominant AAT Epitope.


More Definitions of Epitope

Epitope means Epitope, Inc., an Oregon corporation.
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Related to Epitope

  • Receptor means enclosed spaces, conduits, protected groundwater sources, drinking and non-drinking water wells, surface water bodies, and public water systems which when impacted by chemicals of concern may result in exposure to humans and aquatic life, explosive conditions or other adverse effects on health, safety and the environment as specified in these rules.

  • coronavirus means severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);

  • Preceptor means an individual who provides, directs, or verifies training and experience required for an individual to become an authorized user, an authorized medical physicist, an authorized nuclear pharmacist, or a radiation safety officer.

  • Antigen means a substance recognized by the body as being foreign; it results in the production of specific antibodies directed against it.

  • Halogen means one of the chemical elements chlorine, bromine or iodine.

  • DNA means deoxyribonucleic acid.

  • Antibody means a molecule or a gene encoding such a molecule comprising or containing one or more immunoglobulin variable domains or parts of such domains or any existing or future fragments, variants, modifications or derivatives thereof.

  • Opioid antagonist means a drug that binds to opioid

  • Cannabinoid means any of the chemical compounds that are the active constituents of marijuana.

  • Corrosion inhibitor means a substance capable of reducing the corrosivity of water toward metal plumbing materials, especially lead and copper, by forming a protective film on the interior surface of those materials.

  • Biological agent shall mean any pathogenic (disease producing) micro-organism(s) and/or biologically produced toxin(s) (including genetically modified organisms and chemically synthesized toxins) which cause illness and/or death in humans, animals or plants.

  • Isomer means all enantiomers and diastereomers.

  • genocide means any of the following acts committed with intent to destroy, in whole or in part, a national, ethnical, racial or religious group, as such:

  • Cannabinoid edible means food or potable liquid into which a cannabinoid concentrate, cannabinoid extract or dried marijuana leaves or flowers have been incorporated.

  • Pyrolysis means the thermal degradation of a substance in the absence of any oxidising agent, which does not form part of the substance itself, to produce char and gas and/or liquid; and

  • Precursor means any chemical reactant which takes part at any stage in the production by whatever method of a toxic chemical. This includes any key component of a binary or multicomponent chemical system.

  • Bioassay means the determination of kinds, quantities or concentrations and, in some cases, the locations of radioactive material in the human body, whether by direct measurement, in vivo counting, or by analysis and evaluation of materials excreted or removed from the human body. For purposes of these rules, “radiobioassay” is an equivalent term.

  • Brachytherapy source means a radioactive source or a manufacturer-assembled source train or a combination of these sources that is designed to deliver a therapeutic dose within a distance of a few centimeters.

  • Radionuclide means a radioactive element or a radioactive isotope.

  • Biological Samples means any physical samples obtained from Study Participants in accordance with the Protocol for the purposes of the Study.

  • Vaccine means a specially prepared antigen which, upon administration to a person, will result in immunity and, specifically for the purposes of this rule, shall mean influenza and pneumococcal vaccines.

  • Electrostatic spray means a method of applying a spray coating in which opposite electric charges are applied to the substrate and the coating. The coating is attracted to the substrate by the electrostatic potential between them.

  • Cannabidiol means a finished preparation containing, of its total cannabinoid content, at least 98 percent cannabidiol and not more than 0.90 percent tetrahydrocannabinol by volume that has been extracted from marijuana or synthesized in a laboratory.

  • Cannabinoid extract means a substance obtained by separating cannabinoids from marijuana by:

  • Progeny means unmodified descendant from the Material, such as virus from virus, cell from cell, or organism from organism.

  • Chemical agent shall mean any compound which, when suitably disseminated, produces incapacitating, damaging or lethal effects on people, animals, plants or material property.