CB2 definition
Examples of CB2 in a sentence
Group C-B Certificates The Class C-B-1, Class C-B-2, Class C-B-3, Class C-B-4, Class C-B-5 and Class C-B-6 Certificates.
The endocannabinoid system (ECS) is a widely distributed signaling system in the brain, involving cannabinoid receptors 1 and 2 (CB1 and CB2) and their best known endogenous agonists N-arachidonoyl ethanolamine (anandamide, AEA) and 2-arachidonoyl glycerol (2- AG), which are defined as endocannabinoids (eCBs)1.
Group C-B Certificates: The Class C-B-1, Class C-B-2, Class C-B-3, Class C-B-4, Class C-B-5 and Class C-B-6 Certificates.
You will be based at the CUSU offices in Cambridge (Old Examination Hall, Free School Lane, Cambridge CB2 3RF) [or alternative offices as would be identified as the offices of the CUSU], although frequently you will be required to work elsewhere in the University of Cambridge and its constituent Colleges.
Subordinate Certificate: Any of the Class C-B-1, Class C-B-2, Class C-B-3, Class C-B-4, Class C-B-5, Class C-B-6, Class 1-B-1 or Class 1-B-2 Certificates.
The Class C-B-1, Class C-B-2, Class C-B-3, Class C-B-4, Class C-B-5 and Class C-B-6 Certificates.
CB2 plays a central role in modulating and resolving inflammation by, in effect, turning heightened inflammation “off” and restoring homeostasis.
Our lead investigational drug candidate, lenabasum, is a novel, synthetic, oral, cannabinoid type 2, or CB2, agonist designed to resolve chronic inflammation, limit fibrosis and support tissue repair.
Lenabasum selectively binds to CB2 in the periphery, which is preferentially expressed on activated immune cells, fibroblasts and other cell types, including muscle and bone cells.
This has been demonstrated in animal models lacking CB2 as well as humans with genetic polymorphism in the CB2 gene, as these exhibit excessive inflammation and fibrosis in response to activators of the innate immune system.