Rider To License Agreement Sample Contracts

Confidential Materials Omitted and Filed Separately With the Securities and Exchange Commission. Double Asterisks Denote Omissions. RIDER TO LICENSE AGREEMENT (March 31st, 2014)

Argos Therapeutics, Inc., a corporation organized and existing under the laws of Delaware (Argos), and Medinet Co., Ltd., a corporation organized and existing under the laws of Japan (Medinet) desire to amend that certain License Agreement as of December 27, 2013 (the Agreement) with the addition of this Rider.