0001114220-17-000006 Sample Contracts

Master Manufacturing Services Agreement September 27, 2016
Product Agreement • March 1st, 2017 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations • New York

THIS AGREEMENT WITNESSES THAT in consideration of the rights conferred and the obligations assumed herein, and for other good and valuable consideration (the receipt and sufficiency of which are acknowledged by each party), and intending to be legally bound the parties agree as follows:

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AMENDMENT TWO TO EMPLOYMENT AGREEMENT
Employment Agreement • March 1st, 2017 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations

This Amendment Number Two (the “Amendment”) to the Employment Agreement dated June 26, 2015, as amended by Amendment Number One to the Employment Agreement dated October 15, 2015 (the Employment Agreement, as amended, referred to herein as the “Employment Agreement”) is made and entered into this 6th day of January, 2017 by and between Keryx Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), and Scott Holmes (“Executive”), to be effective immediately.

AMENDMENT TWO TO EMPLOYMENT AGREEMENT
Employment Agreement • March 1st, 2017 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations

This Amendment Number Two (the “Amendment”) to the Employment Agreement dated April 8, 2014, as amended by Amendment Number One to the Employment Agreement dated October 15, 2015 (the Employment Agreement, as amended, referred to herein as the “Employment Agreement”) is made and entered into this 15th day of December, 2016 by and between Keryx Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), and Brian Adams (“Executive”), to be effective immediately.

AMENDMENT TWO TO EMPLOYMENT AGREEMENT
Employment Agreement • March 1st, 2017 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations

This Amendment Number Two (the “Amendment”) to the Employment Agreement dated April 22, 2015, as amended by Amendment Number One to the Employment Agreement dated October 15, 2015 (the Employment Agreement, as amended, referred to herein as the “Employment Agreement”) is made and entered into this 6th day of January, 2017 by and between Keryx Biopharmaceuticals, Inc., a Delaware corporation (the “Company”), and John F. Neylan, MD (“Executive”), to be effective immediately.

ONE MARINA PARK DRIVE OFFICE LEASE
Drive Office Lease • March 1st, 2017 • Keryx Biopharmaceuticals Inc • Pharmaceutical preparations • Massachusetts

THIS LEASE (this “Lease”), made as of April 29, 2015, by and between FALLON CORNERSTONE ONE MPD LLC, a Delaware limited liability company (“Landlord”), and KERYX BIOPHARMACEUTICALS, INC., a Delaware corporation (“Tenant”).

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