0001104659-08-061943 Sample Contracts

STANDBY EQUITY DISTRIBUTION AGREEMENT
Equity Distribution Agreement • October 3rd, 2008 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • New Jersey

THIS AGREEMENT dated as of the 29th day of September 2008 (this “Agreement”) between YA GLOBAL INVESTMENTS, L.P., a Cayman Islands exempt limited partnership (the “Investor”), and ADVANCED LIFE SCIENCES HOLDINGS, INC., a corporation organized and existing under the laws of the State of Delaware (the “Company”).

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STOCK PURCHASE AGREEMENT
Stock Purchase Agreement • October 3rd, 2008 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • New York

THIS STOCK PURCHASE AGREEMENT (this “Agreement”) is entered into as of this 29th day of September, 2008 by and between ADVANCED LIFE SCIENCES HOLDINGS, INC., a Delaware corporation (the “Company”), and WYETH, a Delaware corporation (the “Investor”).

REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • October 3rd, 2008 • Advanced Life Sciences Holdings, Inc. • Biological products, (no disgnostic substances) • New Jersey

REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of the 29th day of September 2008 (this “Agreement”) between YA GLOBAL INVESTMENTS, L.P., a Cayman Islands exempt limited partnership (the “Investor”), and ADVANCED LIFE SCIENCES HOLDINGS, INC., a corporation organized and existing under the laws of the State of Delaware (the “Company”)

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