0001078782-12-000060 Sample Contracts

DATED 22 September 2010 SINGAPORE VOLITION Pte LIMITED and VALIRX PLC
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels)

ValiRx PLC (incorporated and registered in England and Wales under company number 3916791 the registered office of which is at 24 Greville Street, London EC1N 8SS (the "Seller"); and

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Patent License Agreement
Patent License Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)
THIS AMENDING AGREEMENT dated 31 July 2006 is between:
Amending Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)
Agreement no. 5852 relative to a repayable advance on the diagnosis of colorectal cancer by nucleosomics.
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels) • Wallonia
Patent Licence Agreement
Patent Licence Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

Certain patents, intellectual property, know-how and technical data collectively known as the Intellectual Property Rights (IPR) were licensed to ValiRx PLC (ValiRx) through the Patent License Agreement dated 03 October 2007 from Chroma Therapeutics Limited, a Company registered in England and Wales under Company number 04066289 whose principal place of business is 93 Milton Park, Abingdon, Oxon OX14 4RY.

Patent Licence Agreement
Patent Licence Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels) • England and Wales

Certain patents, intellectual property, know-how and technical data collectively known as the Intellectual Property Rights (IPR) were licensed to ValiPharma (formally known as Cronos Therapeutics Ltd) through the Patent License Agreement (as amended) dated 19 October 2005 from Imperial Innovations Limited (formerly known as Imperial College Innovations Limited), a Company registered in England and Wales under Company number 02060639 whose principal place of business is 52 Princess Gate, Exhibition Road, London, SW7 2PG.

DATED______________________________________________________________________2012
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels)

IMPERIAL INNOVATIONS LIMITED incorporated and registered in England and Wales with company number 02060639 whose registered office is at 52 Princess Gate, Exhibition Road, London, SW7 2PG (“Innovations”);

Volition Research Limited 82Z Portland Place London, W1B 1NS Dear Sirs
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels)

Under the terms of the Service Agreement dated [Date] 2011 between Singapore Volition Pte. Limited (“Volition”) and Volition Research Ltd (“Research”), Volition has a debt owing to Research in the amount of US$105,000.00 (the “Debt”) for the provision of business development services over the period of the Agreement.

License Agreement Non-exploitation and third party patent
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels)

Chroma Therapeutics Limited, 92, Milton Park Abington, Oxfordshire OX14 4RY, UK is the owner of the patent WO 2005/019826 A1, 3 March 2005 entitled "Detection of Histone Modification in Cell-Free Nucleosomes”

THIS AGREEMENT dated the 06th day of August 2010 is BETWEEN:
Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

SINGAPORE VOLITION PTE LIMITED a private limited company incorporated and registered in Singapore with registration number 201016543R and whose principal address is 165 Gangsa Road, Unit 01-70, Singapore, 670165 (hereinafter "SV")

THIS AGREEMENT dated October 3rd 2007 is between: RECITALS:
Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

Chroma has developed and owns a technology relating to chromatin, necleosome and histone structure and the determination of histone modifications particularly as the basis of methods for the diagnosis, prognosis and monitoring of cancer and other diseases (the “Technology”).

THIS AGREEMENT dated the 10 day of August 2011 is BETWEEN:
Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

SINGAPORE VOLITION PTE LIMITED a private limited company incorporated and registered in Singapore with registration number 201016543R and whose principal address is 150 Orchard Road, Orchard Plaza, 08-02, Singapore, 238841 (hereinafter "VOLITION")

LICENSE AGREEMENT
License Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

This License Agreement (hereinafter the “Agreement”) is made effective the date of full execution (hereinafter the “Effective Date”), by and between:

SUPPLEMENTARY AGREEMENT TO THE SHARE PURCHASE AGREEMENT
Supplementary Agreement • January 11th, 2012 • Volitionrx LTD • Mining & quarrying of nonmetallic minerals (no fuels)

VALIRX PLC incorporated and registered in England and Wales under company number 3916791 the registered office of which is at 24 Greville Street, London EC1N 8SS (the “Seller”); and

Malcolm Lewin Old Manor House, South Side, Steeple Aston, Oxfordshire, OX25 4RR, United Kingdom Dear Mr. Lewin Consultancy agreement
Volitionrx LTD • January 11th, 2012 • Mining & quarrying of nonmetallic minerals (no fuels)

We are writing to confirm the terms of our agreement concerning the provision of your consultancy services to Singapore Volition Pte. Limited (the “Company”).

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