0000950123-18-006464 Sample Contracts

CONFIDENTIAL EXECUTION COPY
Confidential       Execution • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • New York

THIS AMENDED AND RESTATED OPTION, LICENSE, AND COLLABORATION AGREEMENT (“Agreement”) is made and entered into, effective as of November 8, 2017 (“A&R Effective Date”), by and between ARVINAS, INC., having its principal place of business at 5 Science Park, 395 Winchester Ave., New Haven, CT 06511 (“Arvinas”), and GENENTECH, INC., a Delaware corporation, having its principal place of business at 1 DNA Way, South San Francisco, California 94080 (“Genentech”), and as expressly provided herein as a “Licensee” or as a “Party,” or as expressly named herein under Section 9.6, F. Hoffmann-La Roche Ltd, with its principal place of business at Grenzacherstrasse 124, CH 4070 Basel, Switzerland (“Roche”).

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ARVINAS HOLDING COMPANY, LLC SECOND AMENDED AND RESTATED OPERATING AGREEMENT DATED AS OF MARCH 29, 2018 A LIMITED LIABILITY COMPANY ORGANIZED UNDER THE DELAWARE LIMITED LIABILITY COMPANY ACT
Operating Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Delaware

This Second Amended and Restated Operating Agreement, dated as of March 29, 2018 (as amended from time to time in accordance with the terms hereof, this “Agreement”), is by and among Arvinas Holding Company, LLC, a Delaware limited liability company (the “LLC”), and the persons identified as the Members on Schedule A attached hereto (such persons and their respective successors and permitted assigns being hereinafter referred to individually as a “Member” or collectively as the “Members”), as such Schedule A may hereinafter be amended.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. SPONSORED RESEARCH AGREEMENT
Sponsored Research Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • New York

THIS SPONSORED RESEARCH AGREEMENT (this “Agreement”) dated as of March 7, 2018 (the “Effective Date”), is entered into between The Silverstein Foundation For Parkinson’s With GBA, a Delaware corporation (the “TSF”) and Arvinas, Inc., a Delaware corporation (“Company”), having a place of business located at 5 Science Park, New Haven, CT 06511.

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. RESEARCH COLLABORATION AND LICENSE AGREEMENT by and between ARVINAS, INC. and PFIZER INC.
Collaboration and License Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Delaware

This Agreement (this “Agreement”) is effective as of December 22, 2017 (the “Effective Date”), and is entered into by and between Arvinas, Inc., a corporation organized and existing under the laws of Delaware, located at 5 Science Park, 395 Winchester Ave., New Haven, CT 06511 (“Arvinas”) and Pfizer Inc., a corporation organized and existing under the laws of Delaware, located at 235 East 42nd Street, New York, NY 10017 (“Pfizer”).

LEASE BETWEEN SCIENCE PARK DEVELOPMENT CORPORATION AND ARVINAS, INC.
Lease • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Connecticut

This Lease (this “Lease”) is made and entered into as of the day of ____ December, 2017, by and between SCIENCE PARK DEVELOPMENT CORPORATION, a Connecticut corporation having a principal place of business at 5 Science Park, New Haven, Connecticut 06511 (herein referred to as “Landlord”) and ARVINAS, INC., a Delaware corporation having a principal place of business at 5 Science Park, New Haven, Connecticut 06511 (herein referred to as “Tenant”).

ARVINAS HOLDING COMPANY, LLC AWARD AGREEMENT
Award Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Delaware

THIS ARVINAS HOLDING COMPANY, LLC AWARD AGREEMENT (this “Agreement”) is made as of , by and between Arvinas Holding Company, LLC, a Delaware limited liability company (the “Company”) and «Name» (the “Recipient”).

Confidential Materials omitted and filed separately with the Securities and Exchange Commission. Double asterisks denote omissions. YALE UNIVERSITY CORPORATE SPONSORED RESEARCH AGREEMENT
Corporate Sponsored Research Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Connecticut

This is a CORPORATE SPONSORED RESEARCH AGREEMENT effective July 1, 2016, by and between YALE UNIVERSITY, a non-profit corporation organized and existing under and by virtue of a special charter granted by the General Assembly of the Colony and State of Connecticut (the “University”) and Arvinas, Inc., a Delaware corporation, having its principal offices at 5 Science Park, 395 Winchester Avenue, New Haven, CT 06511 (the “Sponsor”).

AMENDED AND RESTATED CONSULTING AGREEMENT
Consulting Agreement • June 22nd, 2018 • Arvinas Holding Company, LLC • Pharmaceutical preparations • Connecticut

This Amended and Restated Consulting Agreement (this “Agreement”) is effective as of October 16, 2015 (the “Effective Date”), by and between Arvinas, Inc., a Delaware corporation (the “Company”) and Dr. Craig Crews (the “Consultant”) and amends and restates, in its entirety, the Consulting Agreement effective as of July 8, 2013 by and between the Company and the Consultant (the “Existing Agreement”).

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