Delcath Systems, Inc. Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • December 13th, 2022 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of December 7, 2022, between Delcath Systems, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).

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REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • December 13th, 2022 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus

This Registration Rights Agreement (this “Agreement”) is made and entered into as of December 7, 2022, by and between Delcath Systems, Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”).

OF
Delcath Systems Inc • November 30th, 2005 • Surgical & medical instruments & apparatus • New York
Units, each Unit Consisting of Five Shares of Common Stock and Five Redeemable Common Stock Purchase Warrants Each to Purchase One Share of
Underwriting Agreement • March 17th, 2003 • Delcath Systems Inc • Services-commercial physical & biological research • Delaware
RECITALS
Employment Agreement • July 5th, 2007 • Delcath Systems Inc • Surgical & medical instruments & apparatus • New York
AGREEMENT
Common Stock Purchase Agreement • November 30th, 2005 • Delcath Systems Inc • Surgical & medical instruments & apparatus • New York
PRE-FUNDED COMMON STOCK PURCHASE WARRANT DELCATH SYSTEMS, INC.
Delcath Systems, Inc. • February 7th, 2020 • Surgical & medical instruments & apparatus • New York

THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and until this Warrant is exercised in full (the “Termination Date”) but not thereafter, to subscribe for and purchase from Delcath Systems, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

OF
Delcath Systems Inc • December 1st, 2004 • Services-commercial physical & biological research • New York
VOTING AGREEMENT
Voting Agreement • November 30th, 2005 • Delcath Systems Inc • Surgical & medical instruments & apparatus
SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • July 20th, 2022 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of July 18, 2022, between Delcath Systems, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”).

DELCATH SYSTEMS, INC. Shares of Common Stock (par value $0.01 per share) Controlled Equity OfferingSM Sales Agreement
Sales Agreement • August 18th, 2020 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

Delcath Systems, Inc., a Delaware corporation (the “Company”), confirms its agreement (this “Agreement”) with Cantor Fitzgerald & Co. (the “Agent”), as follows:

OF
Delcath Systems Inc • November 30th, 2005 • Surgical & medical instruments & apparatus • New York
MODIFICATION AGREEMENT
Modification Agreement • April 16th, 2007 • Delcath Systems Inc • Surgical & medical instruments & apparatus
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FORM OF PRE-FUNDED COMMON STOCK PURCHASE WARRANT DELCATH SYSTEMS, INC.
Delcath Systems, Inc. • December 13th, 2022 • Surgical & medical instruments & apparatus

THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, [____] or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and UNTIL THIS Warrant is exercised in full (the “Termination Date”) but not thereafter, to subscribe for and purchase from Delcath Systems, Inc., a Delaware corporation (the “Company”), up to [___] shares of Common Stock (as subject to adjustment hereunder, the “Warrant Shares”). The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

AMENDED AND RESTATED SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • July 12th, 2017 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

This AMENDED AND RESTATED SECURITIES PURCHASE AGREEMENT (this “Agreement”), dated as of July 5, 2017, is by and among Delcath Systems, Inc., a Delaware corporation with offices located at 1633 Broadway, Suite 22C, New York, New York 10019 (the “Company”), and each of the investors listed on the Schedule of Buyers attached hereto (individually, a “Buyer” and collectively, the “Buyers”).

and
Rights Agreement • November 14th, 2001 • Delcath Systems Inc • Services-commercial physical & biological research • Delaware
DELCATH SYSTEMS, INC. UNDERWRITING AGREEMENT [•] Shares of Common Stock [•] Pre-Funded Warrants to Purchase Up to [•] Shares of Common Stock Series F Warrants to Purchase Up to [•] Shares of Common Stock
Underwriting Agreement • April 20th, 2020 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

Delcath Systems, Inc., a Delaware corporation (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell to the underwriters named in Schedule I hereto (the “Underwriters,” or each, an “Underwriter”), for whom Roth Capital Partners, LLC is acting as the representative (the “Representative”), (i) an aggregate of [•] authorized but unissued shares (the “Firm Shares”) of Common Stock, par value $0.01 per share, of the Company (the “Common Stock”), (ii) pre-funded warrants (the “Pre-Funded Warrants”) to purchase up to an aggregate of [•] shares of Common Stock at an exercise price of $0.01 per share (the “Pre-Funded Warrant Shares”), and (iii) Series F warrants (the “Firm Warrants”) to purchase up to an aggregate of [•] shares of Common Stock (the “Firm Warrant Shares”). The Firm Shares, the Pre-Funded Warrants, the Pre-Funded Warrant Shares, the Firm Warrants and the Firm Warrant Shares are collectively referred to as the “Firm Securities.” The Company

and AMERICAN STOCK TRANSFER & TRUST COMPANY Warrant Agent
Warrant Agent Agreement • August 11th, 2005 • Delcath Systems Inc • Surgical & medical instruments & apparatus • New York
PLACEMENT AGENCY AGREEMENT
Placement Agency Agreement • January 17th, 2018 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York
Delcath Systems, Inc. and American Stock Transfer & Trust Company, LLC, as Warrant Agent Warrant Agency Agreement Dated as of April __, 2020
Warrant Agency Agreement • April 20th, 2020 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

WARRANT AGENCY AGREEMENT, dated as of April __, 2020 (“Agreement”), between Delcath Systems, Inc., a Delaware corporation (the “Company”), and American Stock Transfer & Trust Company, LLC, a New York limited liability trust company (the “Warrant Agent”).

425,000 SHARES OF COMMON STOCK AND 148,750 WARRANTS OF DELCATH SYSTEMS, INC. UNDERWRITING AGREEMENT
Underwriting Agreement • October 4th, 2016 • Delcath Systems, Inc. • Surgical & medical instruments & apparatus • New York

The undersigned, Delcath Systems, Inc., a company incorporated under the laws of Delaware (collectively with its subsidiaries and affiliates, including, without limitation, all entities disclosed or described in the Registration Statement as being subsidiaries or affiliates of the Delcath Systems, Inc., the “Company”), hereby confirms its agreement (this “Agreement”) with the several underwriters (such underwriters, including the Representative (as defined below), the “Underwriters” and each an “Underwriter”) named in Schedule I hereto for which Roth Capital Partners, LLC is acting as representative to the several Underwriters (the “Representative” and if there are no Underwriters other than the Representative, references to multiple Underwriters shall be disregarded and the term Representative as used herein shall have the same meaning as Underwriter) on the terms and conditions set forth herein.

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