Nightstar Therapeutics PLC Sample Contracts

Nightstar Therapeutics plc [●] American Depositary Shares Representing [●] Ordinary Shares (Nominal Value £0.01 Per Share) UNDERWRITING AGREEMENT
Underwriting Agreement • September 15th, 2017 • Nightstar Therapeutics LTD • Biological products, (no disgnostic substances) • New York
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DEPOSIT AGREEMENT by and among
Deposit Agreement • April 3rd, 2018 • Nightstar Therapeutics PLC • Biological products, (no disgnostic substances) • New York

DEPOSIT AGREEMENT, dated as of September 27, 2017, by and among (i) NIGHTSTAR THERAPEUTICS PLC, a public limited company incorporated under the laws of England and Wales, and its successors (the “Company”), (ii) CITIBANK, N.A., a national banking association organized under the laws of the United States of America (“Citibank”) acting in its capacity as depositary, and any successor depositary hereunder (Citibank in such capacity, the “Depositary”), and (iii) all Holders and Beneficial Owners of American Depositary Shares issued hereunder (all such capitalized terms as hereinafter defined).

DEPOSIT AGREEMENT by and among NIGHTSTAR THERAPEUTICS PLC And CITIBANK, N.A., as Depositary, and THE HOLDERS AND BENEFICIAL OWNERS OF AMERICAN DEPOSITARY SHARES ISSUED HEREUNDER Dated as of September 27, 2017
Deposit Agreement • October 18th, 2017 • Nightstar Therapeutics PLC • Biological products, (no disgnostic substances) • New York

DEPOSIT AGREEMENT, dated as of September 27, 2017, by and among (i) NIGHTSTAR THERAPEUTICS PLC, a public limited company incorporated under the laws of England and Wales, and its successors (the “Company”), (ii) CITIBANK, N.A., a national banking association organized under the laws of the United States of America (“Citibank”) acting in its capacity as depositary, and any successor depositary hereunder (Citibank in such capacity, the “Depositary”), and (iii) all Holders and Beneficial Owners of American Depositary Shares issued hereunder (all such capitalized terms as hereinafter defined).

Contract
Agreement • September 15th, 2017 • Nightstar Therapeutics LTD • Biological products, (no disgnostic substances)

[*] = Certain confidential information contained in this document, marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended.

AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • March 18th, 2019 • Nightstar Therapeutics PLC • Biological products, (no disgnostic substances) • Massachusetts

This AMENDED AND RESTATED EMPLOYMENT AGREEMENT (the “Agreement”), dated and entered into as of the 20th day of October, 2017 (“Effective Date”), by and between Nightstar, Inc., a Delaware corporation and wholly owned subsidiary of Nightstar Therapeutics plc, a company incorporated under the laws of England and Wales (hereinafter referred to together as the “Company”), and Gregory Robinson (the “Employee”).

NIGHTSTARX LIMITED EMPLOYMENT AGREEMENT
Employment Agreement • March 18th, 2019 • Nightstar Therapeutics PLC • Biological products, (no disgnostic substances) • Massachusetts

AGREEMENT, dated and entered into as of the 1st day of June, 2017 (“Effective Date”), by and between NightstaRx Limited, a company registered in England and Wales (the “Company”), and Tuyen Ong, (the “Employee”).

IMPLEMENTATION AGREEMENT Skadden, Arps, Slate, Meagher & Flom (UK) LLP 40 Bank Street Canary Wharf London E14 5DS
Nightstar Therapeutics PLC • March 4th, 2019 • Biological products, (no disgnostic substances)
EMPLOYMENT AGREEMENT
Employment Agreement • March 18th, 2019 • Nightstar Therapeutics PLC • Biological products, (no disgnostic substances) • Massachusetts

This EMPLOYMENT AGREEMENT (the "Agreement"), dated and entered into as of the 29th day of September, 2017 ("Effective Date"), by and between Nightstar, Inc., a Delaware corporation and wholly owned subsidiary of Nightstar Therapeutics Limited, a company incorporated under the laws of England and Wales (hereinafter referred to together as the "Company"), and Seokho Bryan Yoon (the "Employee").

Contract
Non-Exclusive Patent Licence Agreement • August 28th, 2017 • Nightstar Therapeutics LTD • Biological products, (no disgnostic substances)

[*] = Certain confidential information contained in this document, marked by brackets, is filed with the Securities and Exchange Commission pursuant to Rule 406 of the Securities Act of 1933, as amended.

DATED 12th October 2017
Nightstar Therapeutics PLC • April 3rd, 2018 • Biological products, (no disgnostic substances)

• Licensee is a private biopharmaceutical company focused on the development of therapies for inherited retinal dystrophies.

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