S1 Biopharma, Inc. Sample Contracts

PURCHASE AGREEMENT S1 BIOPHARMA, INC. 2,750,000 Shares(1) Common Stock
Purchase Agreement • November 10th, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • New York
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PURCHASE AGREEMENT S1 BIOPHARMA, INC. 1,750,000 Units(1) Each Unit Consisting of One Share of Common Stock, a Series A Warrant to Purchase One Share of Common Stock and a Series B Warrant to Purchase One Share of Common Stock
Purchase Agreement • November 26th, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • New York

to any of the Undersigned’s Securities or with respect to any security that includes, relates to or derives any significant part of its value from such Securities.

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INDEMNIFICATION AGREEMENT
Indemnification Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (the “Agreement”) is entered into as of , 2014, by and among S1 Biopharma, Inc., a Delaware corporation (the “Company”) and the undersigned party (the “Indemnitee”).

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S1 BIOPHARMA, INC. AMENDED AND RESTATED EMPLOYMENT AGREEMENT
Employment Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

THIS AMENDED AND RESTATED EMPLOYMENT AGREEMENT (this “Agreement”) is made as of June 5, 2014, but effective as of April 5, 2012 (the “Effective Date”), by and between Robert E. Pyke, a resident of New Fairfield, Connecticut (the “Employee”), and S1 Biopharma, Inc., a corporation organized and existing under the laws of the State of Delaware (the “Company”).

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SERIES B WARRANT AGREEMENT S1 Biopharma, Inc. and , as Warrant Agent SERIES B WARRANT AGREEMENT
Series B Warrant Agreement • November 26th, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • New York

THIS SERIES B WARRANT AGREEMENT (this “Agreement”), dated as of , 2014, is by and between S1 Biopharma, Inc., a Delaware corporation (the “Company”), and , a , as Warrant Agent (the “Warrant Agent “).

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SERIES A WARRANT AGREEMENT S1 Biopharma, Inc. and , as Warrant Agent SERIES A WARRANT AGREEMENT
Series a Warrant Agreement • November 26th, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • New York

THIS SERIES A WARRANT AGREEMENT (this “Agreement”), dated as of , 2014, is by and between S1 Biopharma, Inc., a Delaware corporation (the “Company”), and , a , as Warrant Agent (the “Warrant Agent”).

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DIRECTOR COMPENSATION AGREEMENT
Director Compensation Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

THIS DIRECTOR COMPENSATION AGREEMENT (this “Agreement”), dated as of , is entered into by and between S1 Biopharma, Inc., a Delaware corporation (the “Company”), and (the “Director”).

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ADVISORY BOARD CONSULTING AGREEMENT
Advisory Board Consulting Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Florida

THIS ADVISORY BOARD CONSULTING AGREEMENT (“Agreement”), made this th day of , 2012, is entered into by S1 Biopharma, Inc., a Delaware corporation (“Company”), and (“Advisor”).

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CONSULTING AGREEMENT
Consulting Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations

Levine, Risen and Associates, Inc. (The Center for Marital and Sexual Health Inc.), 23425 Commerce Park Rd. Suite 104, Beachwood, Ohio 44122 216-831-2900 [sheridan@levinerisenandassociates.com]

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S1 BIOPHARMA, INC. NON-QUALIFIED STOCK OPTION AGREEMENT
Non-Qualified Stock Option Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

S1 Biopharma, Inc. (the “Company”) hereby grants to [ ] (the “Optionee”) an option (the “Option”) to purchase a total of [ ] shares of Common Stock of the Company (the “Option Shares”), at the price and on the terms set forth herein, and in all respects subject to the terms, definitions and provisions of the S1 Biopharma, Inc. 2014 Equity Incentive Plan (the “Plan”) applicable to non-qualified stock options, which terms and provisions are hereby incorporated by reference herein. Unless the context herein otherwise requires, the terms defined in the Plan shall have the same meanings when used herein.

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AWARD AGREEMENT FOR RESTRICTED SHARES UNDER THE S1 BIOPHARMA, INC.
Award Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

THIS AWARD AGREEMENT FOR RESTRICTED SHARES (this “Agreement”) is made between S1 Biopharma, Inc. (the “Company”) and (the “Grantee”), dated , 201 (the “Effective Date”).

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CONSULTING AGREEMENT
Consulting Agreement • October 1st, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • Delaware

NOW THEREFORE, in consideration of the premises, the mutual covenants and agreements set forth in this Agreement and other good and valuable consideration, the receipt and sufficiency of which is hereby acknowledged by each of the parties, the parties hereby agree as follows:

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S1 BIOPHARMA, INC. COMMON STOCK WARRANT
Common Stock Warrant • November 26th, 2014 • S1 Biopharma, Inc. • Pharmaceutical preparations • New York

This Common Stock Warrant (this “Warrant”) certifies that, for value received, the Holder is entitled to purchase, and S1 Biopharma, Inc., a Delaware corporation (the “Company”), promises and agrees to sell and issue to the Holder, at any time, or from time to time, during the Exercise Period, up to shares of Common Stock of the Company, par value $0.0001 per share (the “Common Stock”), at the Exercise Price, subject to the provisions and upon the terms and conditions hereinafter set forth.

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