Genprex, Inc. Sample Contracts

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • November 22nd, 2019 • Genprex, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of November 20, 2019, between Genprex, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

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REGISTRATION RIGHTS AGREEMENT
Registration Rights Agreement • May 10th, 2018 • Genprex, Inc. • Pharmaceutical preparations

This Registration Rights Agreement (this “Agreement”) is made and entered into as of May 6, 2018, between Genprex, Inc., a Delaware corporation (the “Company”), and each of the several purchasers signatory hereto (each such purchaser, a “Purchaser” and, collectively, the “Purchasers”).

GENPREX, INC. AMENDED AND RESTATED UNDERWRITING AGREEMENT
Underwriting Agreement • December 12th, 2017 • Genprex, Inc. • Pharmaceutical preparations • New York

Genprex, Inc., a corporation organized and existing under the laws of State of Delaware (the “Company”), agrees, subject to the terms and conditions of this agreement (this “Agreement”) to issue and sell to Network 1 Financial Securities, Inc. (“Network 1” or the “Underwriter”) an aggregate of one million three hundred thousand (1,300,000) shares of common stock (the “Firm Shares”), par value $0.001 per share, of the Company (the “Common Stock”). At the option of the Underwriter, the Company agrees, subject to the terms and conditions herein, to issue and sell up to an aggregate of 195,000 additional shares of Common Stock (the “Option Shares”). The Firm Shares and the Option Shares are herein referred to collectively as the “Securities”.

COMMON STOCK PURCHASE WARRANT GENPREX, INC.
Common Stock Purchase Warrant • July 19th, 2023 • Genprex, Inc. • Pharmaceutical preparations

THIS COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on July 21, 2028 (the “Termination Date”) but not thereafter, to subscribe for and purchase from Genprex, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

GENPREX, INC., Issuer AND [TRUSTEE], Trustee INDENTURE Dated as of [•], 20__ Debt Securities
Indenture • September 16th, 2019 • Genprex, Inc. • Pharmaceutical preparations • New York

Whereas, for its lawful corporate purposes, the Company has duly authorized the execution and delivery of this Indenture to provide for the issuance of debt securities (hereinafter referred to as the “Securities”), in an unlimited aggregate principal amount to be issued from time to time in one or more series as in this Indenture provided, as registered Securities without coupons, to be authenticated by the certificate of the Trustee;

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • January 17th, 2020 • Genprex, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of January 16, 2020, between Genprex, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • July 19th, 2023 • Genprex, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of July 18, 2023, between Genprex, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

INDEMNITY AGREEMENT
Indemnity Agreement • September 8th, 2017 • Genprex, Inc. • Pharmaceutical preparations • Delaware

THIS INDEMNITY AGREEMENT (this “Agreement”) dated as of , 20 , is made by and between Genprex, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”).

PLACEMENT AGENT COMMON STOCK PURCHASE WARRANT GENPREX, INC.
Genprex, Inc. • July 19th, 2023 • Pharmaceutical preparations

THIS PLACEMENT AGENT COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and on or prior to 5:00 p.m. (New York City time) on July 18, 2028 (the “Termination Date”) but not thereafter, to subscribe for and purchase from Genprex, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b). This Placement Agent Common Stock Purchase Warrant is being issued pursuant to that certain Engagement Agreement between the Company and H.C. Wainwright & Co., LLC, dated as of July 17, 2023.

Genprex, Inc.
Genprex, Inc. • February 9th, 2021 • Pharmaceutical preparations • New York
GENPREX, INC. UNDERWRITING AGREEMENT
Underwriting Agreement • September 8th, 2017 • Genprex, Inc. • Pharmaceutical preparations • New York

Genprex, Inc., a corporation organized and existing under the laws of State of Delaware (the “Company”), proposes to issue and sell to the purchasers, pursuant to the terms and conditions of this Underwriting Agreement (this “Agreement”) and the Subscription Agreements in the form of Exhibit A attached hereto (the “Subscription Agreement”) entered into with the purchasers identified therein (each a “Purchaser” and collectively, the “Purchasers”), a minimum amount (the “Minimum Amount”) of shares of common stock, par value $0.001 per share (the “Common Stock”), of the Company up to a maximum amount (the “Maximum Amount”) of shares of Common Stock (the “Securities”) pursuant to a Registration Statement on Form S-1 declared effective by the United States Securities and Exchange Commission (the “Commission”). The Company hereby confirms its agreement with Network 1 Financial Securities, Inc. (“Network 1” or the “Underwriter”) concerning the purchase and sale of the Securities as follows:

Form of Underwriter’s Warrant Agreement]
Genprex, Inc. • October 10th, 2017 • Pharmaceutical preparations • Texas

THIS PURCHASE WARRANT IS NOT EXERCISABLE PRIOR TO [ ] [DATE THAT IS SIX MONTHS FROM THE CLOSING DATE OF THE OFFERING]. VOID AFTER 5:00 P.M., EASTERN TIME, [ ] [DATE THAT IS FIVE YEARS FROM THE EFFECTIVE DATE (AS DEFINED BELOW) OF THE OFFERING].

Genprex, Inc. Common Stock EQUITY DISTRIBUTION AGREEMENT Dated: November 18, 2022
Equity Distribution Agreement • November 18th, 2022 • Genprex, Inc. • Pharmaceutical preparations • New York
SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • February 9th, 2021 • Genprex, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of February 8, 2021, and is between Genprex, Inc, a corporation incorporated under the laws of the state of Delaware (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

GENPREX, INC. UNDERWRITING AGREEMENT
Underwriting Agreement • October 10th, 2017 • Genprex, Inc. • Pharmaceutical preparations • New York

Genprex, Inc., a corporation organized and existing under the laws of State of Delaware (the “Company”), proposes to issue and sell to the purchasers, pursuant to the terms and conditions of this Underwriting Agreement (this “Agreement”) and the Subscription Agreements in the form of Exhibit A attached hereto (the “Subscription Agreement”) entered into with the purchasers identified therein (each a “Purchaser” and collectively, the “Purchasers”), a minimum amount (the “Minimum Amount”) of 2,500,000 shares of common stock, par value $0.001 per share (the “Common Stock”), of the Company up to a maximum amount (the “Maximum Amount”) of 4,500,000 shares of Common Stock (the “Securities”) pursuant to a Registration Statement on Form S-1 declared effective by the United States Securities and Exchange Commission (the “Commission”). The Company hereby confirms its agreement with Network 1 Financial Securities, Inc. (“Network 1” or the “Underwriter”) concerning the purchase and sale of the Secu

EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 23rd, 2020 • Genprex, Inc. • Pharmaceutical preparations • Texas

This Executive Employment Agreement (the “Agreement”) is entered into between Genprex, Inc. (“Company”) and Catherine Vaczy (“Employee”). This Agreement is effective as of the effective date provided below (“Effective Date”).

Genprex, Inc. Health Discovery Building
Genprex, Inc. • February 20th, 2020 • Pharmaceutical preparations • New York
PRE-FUNDED COMMON STOCK PURCHASE WARRANT GENPREX, INC.
Genprex, Inc. • March 20th, 2024 • Pharmaceutical preparations

THIS PRE-FUNDED COMMON STOCK PURCHASE WARRANT (the “Warrant”) certifies that, for value received, _____________ or its assigns (the “Holder”) is entitled, upon the terms and subject to the limitations on exercise and the conditions hereinafter set forth, at any time on or after the date hereof (the “Initial Exercise Date”) and until this Warrant is exercised in full (the “Termination Date”) but not thereafter, to subscribe for and purchase from Genprex, Inc., a Delaware corporation (the “Company”), up to ______ shares (as subject to adjustment hereunder, the “Warrant Shares”) of Common Stock. The purchase price of one share of Common Stock under this Warrant shall be equal to the Exercise Price, as defined in Section 2(b).

GENPREX, INC. WARRANT AGREEMENT July 27, 2018
Warrant Agreement • August 6th, 2018 • Genprex, Inc. • Pharmaceutical preparations • Delaware

THIS CERTIFIES THAT, for value received, Cancer Revolution LLC or its successors and permitted assigns pursuant to the terms hereof (the “Warrantholder”), is entitled to purchase from Genprex, Inc., a Delaware corporation (the “Company”), subject to the terms set forth below, four hundred twenty-five thousand (425,000) fully paid and non-assessable shares (subject to adjustment as provided herein) (the “Warrant Shares”) of the Company’s common stock, par value $0.001 per share (the “Common Stock”), at a purchase price of $5.00 in cash per Warrant Share (the “Exercise Price”), subject to the provisions and upon the terms and conditions hereinafter set forth. The term “Warrant Agreement” as used herein shall refer to this Warrant Agreement, as the same may be amended or amended and restated.

EXCLUSIVE LICENSE AGREEMENT
Exclusive License Agreement • July 18th, 2023 • Genprex, Inc. • Pharmaceutical preparations

This Exclusive License Agreement (“Agreement”) is made and entered into as of as of the date of the last signature to this Agreement (“Effective Date”), by and between the University of Pittsburgh – Of the Commonwealth System of Higher Education, a non-profit corporation organized and existing under the laws of the Commonwealth of Pennsylvania, with an office at 1st Floor Gardner Steel Conference Center, 130 Thackeray Avenue, Pittsburgh, Pennsylvania 15260 (“University”), and Genprex, Inc., a Delaware corporation, with its principal business at 3300 Bee Cave Road, Suite 650-227, Austin, Texas 78746 (“Licensee”).

SECURITIES PURCHASE AGREEMENT
Securities Purchase Agreement • March 20th, 2024 • Genprex, Inc. • Pharmaceutical preparations • New York

This Securities Purchase Agreement (this “Agreement”) is dated as of March 19, 2024, between Genprex, Inc., a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively the “Purchasers”).

AMENDED AND RESTATED ESCROW DEPOSIT AGREEMENT
Escrow Deposit Agreement • September 22nd, 2017 • Genprex, Inc. • Pharmaceutical preparations • New York

This ESCROW DEPOSIT AGREEMENT (this “Agreement”) dated as of this [ ] day of September 2017, by and among GENPREX, INC., a Delaware corporation (the “Company”), having an address at 100 Congress Avenue, Suite 2000, Austin, Texas 78701, NETWORK 1 FINANCIAL SECURITIES, INC., a New Jersey corporation (the “Underwriter”), having an address at The Galleria, Penthouse, 2 Bridge Avenue, Building 2, Red Bank, NJ 07701, and SIGNATURE BANK (the “Escrow Agent”), a New York State chartered bank, having an office at 565 Fifth Avenue, 12th Floor, New York, New York 10017. All capitalized terms not herein defined shall have the meaning ascribed to them in that certain Preliminary Prospectus, dated September 8, 2017, of the Company, including all attachments, schedules and exhibits thereto (the “Prospectus”) included in Registration Statement on Form S-1 (File No. 333-219386).

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GENPREX, INC. AMENDED AND RESTATED WARRANT AGREEMENT Effective Date: August 10, 2020 (the “Effective Date”) Effective date of Original Warrant: December 17, 2015
Warrant Agreement • March 26th, 2021 • Genprex, Inc. • Pharmaceutical preparations • Delaware

THIS AMENDED AND RESTATED WARRANT AGREEMENT (this “Warrant Agreement”) amends, restates and replaces in its entirety that Warrant Agreement effective as of December 17, 2015, by and between Genprex, Inc. and DABS Advanced Biotech Solutions, LLC, which became exercisable 18 months after December 17, 2015 (the “Original Warrant”). Upon the execution of this Warrant Agreement on behalf of Genprex, Inc. and on behalf of DABS Advanced Biotech Solutions, LLC, the Original Warrant is terminated and cancelled hereby, effective as of the Effective Date set forth above, and replaced in its entirety by this Warrant Agreement.

GENPREX, INC. Amendment No. 1 to Stock Option Agreement
Stock Option Agreement • March 24th, 2020 • Genprex, Inc. • Pharmaceutical preparations • Delaware

This Amendment No. 1 to Stock Option Agreement (this “Amendment”) is made as of March 18, 2020 (the “Effective Date”) by and between Genprex, Inc., a Delaware corporation (the “Company”), and David Friedman (the “Optionee”). Capitalized terms used but not defined herein shall have the respective meanings assigned to them in the Company’s 2018 Equity Incentive Plan (the “Plan”) and the Option Agreement (as defined below) with respect to the Option (as defined below), each of which is made a part of this document.

INDEMNIFICATION AGREEMENT
Indemnification Agreement • August 12th, 2022 • Genprex, Inc. • Pharmaceutical preparations • Delaware

This Indemnification Agreement (“Agreement”) is made as of May 17, 2022 by and between Genprex, Inc., a Delaware corporation (the “Company”), and [•] (“Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement.

GENPREX, INC. WARRANT AGREEMENT Effective as of December 17, 2015
Warrant Agreement • August 18th, 2017 • Genprex, Inc. • Pharmaceutical preparations • Delaware

THIS CERTIFIES THAT, for value received, DABS Advanced Biotech Solutions, LLC, or its successors and permitted assigns pursuant to the terms hereof (the “Warrantholder”), is entitled to purchase from Genprex, Inc., a Delaware corporation (the “Corporation”), subject to the terms set forth below, 15,365 fully paid and non-assessable shares (subject to adjustment as provided herein) (the “Warrant Shares”) of the Corporation’s Non-Voting Common Stock, par value $0.001 per share (the “Non-Voting Common Stock”), at a purchase price of $32.54 in cash per Warrant Share (the “Exercise Price”), subject to the provisions and upon the terms and conditions hereinafter set forth. The term “Warrant Agreement” as used herein shall refer to this Warrant Agreement, as the same may be amended or amended and restated.

GENPREX, INC. SUBSCRIPTION AGREEMENT
Subscription Agreement • September 22nd, 2017 • Genprex, Inc. • Pharmaceutical preparations • New York

This Subscription Agreement (this “Subscription Agreement”) is dated , 2017, by and between the undersigned identified on the Signature Page hereto (the “Investor”) and Genprex, Inc., a Delaware corporation (the “Company”).

MASTER SERVICE AGREEMENT
Master Service Agreement • March 29th, 2018 • Genprex, Inc. • Pharmaceutical preparations • New York

THIS MASTER SERVICE AGREEMENT is made and entered into as of this 9th day of March 2018 (the “Effective Date”), by and between 360 East 88th Street, Unit 2A, New York, NY 10128, and Genprex, Inc, a Delaware Corporation having offices at 100 Congress Avenue, Suite 2000, Austin, TX 78701 (the “Company”).

TECHNOLOGY SUBLICENSE AGREEMENT
Technology Sublicense Agreement • August 18th, 2017 • Genprex, Inc. • Pharmaceutical preparations

This Sublicense Agreement (“Agreement”) is made effective this 7th day of March, 2007, by and between Introgen Therapeutics, Inc., a Delaware corporation (“Sublicensor”), and Introgen Research Institute, Inc., a Texas corporation (“Sublicensee”).

ASSIGNMENT AND COLLABORATION AGREEMENT
Assignment and Collaboration Agreement • August 18th, 2017 • Genprex, Inc. • Pharmaceutical preparations

This Assignment and Collaboration Agreement (“Agreement”) is made effective on the 13th day of April 2009, by and between Assignor and Assignee. For purposes hereof, capitalized terms herein have the meanings set forth on Annex A hereto.

FIRST AMENDMENT TO EXECUTIVE EMPLOYMENT AGREEMENT
Executive Employment Agreement • March 25th, 2021 • Genprex, Inc. • Pharmaceutical preparations • Texas

This First Amendment (the “Amendment”) to the Employment Agreement is dated as of March 24, 2021 and effective as of March 19, 2021 (the “Amendment Effective Date”) and is entered into by and between Genprex, Inc., a Delaware corporation (the “Company”) and Catherine Vaczy (the “Employee”). All capitalized terms used herein but not otherwise defined shall have the meanings set forth in the Employment Agreement (as defined herein).

SEPARATION AGREEMENT
Separation Agreement • April 28th, 2020 • Genprex, Inc. • Pharmaceutical preparations • Texas

This Separation Agreement (the “Agreement”) is entered into by and between Genprex, Inc. (the “Company”) and Julien L. Pham (the “Employee”), as of the date signed by Employee below. This Agreement sets forth the mutual agreement of the Company and Employee regarding Employee’s separation from employment.

PATENT AND TECHNOLOGY LICENSE AGREEMENT
Agreement • August 18th, 2017 • Genprex, Inc. • Pharmaceutical preparations • Texas

THIS AGREEMENT (“AGREEMENT”) is made by and between the BOARD OF REGENTS (“BOARD”) of THE UNIVERSITY OF TEXAS SYSTEM (“SYSTEM”), an agency of the State of Texas, whose address is 201 West 7th Street, Austin, Texas 78701, THE UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER (“MDA”), a component institution of the SYSTEM and INTRON THERAPEUTICS, INC., a Texas corporation having a principal place of business located at 301 Congress, Suite 2025, Austin, Texas 78701 (“LICENSEE”).

TECHNOLOGY SUBLICENSE AGREEMENT
Technology Sublicense Agreement • August 18th, 2017 • Genprex, Inc. • Pharmaceutical preparations

This Sublicense Agreement (“Agreement”) is made effective this 1st day of June, 2011, by and between Convergen LifeSciences, Inc., a Delaware corporation (“Sublicensor”), and Introgen Research Institute, Inc., a Texas corporation (“Sublicensee”).

Genprex and University of Pittsburgh Sign Exclusive License Agreement for Potentially Curative Gene Therapy Candidate for Diabetes
Genprex, Inc. • February 18th, 2020 • Pharmaceutical preparations

● Company licenses patented diabetes gene therapy technology designed by researchers at the University of Pittsburgh

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