EXHIBIT 4.4 PREDIX PHARMACEUTICALS HOLDINGS, INC. FIRST AMENDMENT TO WARRANT This First Amendment (the "Amendment") to the Warrant (the "Warrant"), dated October 30, 2003, by and between Predix Pharmaceuticals Holdings, Inc., a Delaware corporation...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Delaware
INDEX" - The Consumer Price Index (including fruits and vegetables) that is published by the Central Statistics Office (the "OFFICE"). "THE BASIC INDEX" - The Index that was published on September 15, 2004 for the month of August 2004. "LINKED"...Management Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc
WITH [NAME OF EMPLOYEE] (EMPLOYEE COPY)Option Agreement • September 30th, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations • Delaware
EXHIBIT 10.16License Agreement • October 21st, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations
Exhibit 4.5 NEITHER THIS WARRANT NOR THE SECURITIES ISSUABLE UPON EXERCISE OF THIS WARRANT HAVE BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Delaware
EXHIBIT 4.7 THIS WARRANT AND THE SHARES OF CAPITAL STOCK ISSUED UPON ANY EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE SOLD OR...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Delaware
FIRST AMENDMENT TO REGISTRATION RIGHTS AGREEMENTRegistration Rights Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Delaware
WITHIncentive Stock Option Agreement • September 30th, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations • Delaware
WITNESSETH:Stockholders Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Delaware
UNDERWRITING AGREEMENT UNDERWRITING AGREEMENTUnderwriting Agreement • September 30th, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations • New York
LEAS1998* MASTER LEASE AGREEMENT DATED AS OF DECEMBER 3, 2002 ("AGREEMENT") THIS AGREEMENT is between GENERAL ELECTRIC CAPITAL CORPORATION (together with its successors and assigns, if any, "LESSOR") and PREDIX PHARMACEUTICALS, INC. ("LESSEE"). Lessor...Master Lease Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc
WITH DR. OREN BECKEREmployment Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc
FIRST AMENDMENT TO SECOND AMENDED AND RESTATED STOCKHOLDERS AGREEMENT This First Amendment (the "Amendment") to the Second Amended and Restated Stockholders Agreement, dated January 21, 2005, by and between Predix Pharmaceuticals Holdings, Inc., a...Stockholders Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc
EXHIBIT 10.20 Predix Pharmaceuticals PERSONAL AND CONFIDENTIAL January 31, 2005 Dr. Dale Dhanoa [ADDRESS] Dear Dale: The purpose of this letter agreement (the "Agreement") is to describe the terms of your separation from Predix Pharmaceuticals...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005
RECITALSPredix Pharmaceuticals Holdings Inc • August 3rd, 2005 • New Jersey
WITHNonstatutory Stock Option Agreement • September 30th, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations • Delaware
EXHIBIT 4.8 THIS WARRANT AND THE SHARES OF CAPITAL STOCK ISSUED UPON ANY EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE "SECURITIES ACT"), OR ANY APPLICABLE STATE SECURITIES LAWS AND MAY NOT BE SOLD OR...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Delaware
WITNESSETH:Employment Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Massachusetts
1. Purchase of Shares.......................................................... 1 1.1 Purchase of Shares................................................. 1 1.2 Agreement of Sale.................................................. 1 1.3 Options and...Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Delaware
EXHIBIT 10.16License Agreement • September 30th, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations
WITHOption Agreement • October 21st, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations
WITNESSETH:Employment Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Massachusetts
EXHIBIT 10.9 BIO-I.T. (BIO INFORMATION TECHNOLOGIES) LTD. EMPLOYMENT AGREEMENTEscrow Agreement • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc
BETWEENDevelopment and Commercialization Agreement • October 21st, 2005 • Predix Pharmaceuticals Holdings Inc • Pharmaceutical preparations • Maryland
LEASEPredix Pharmaceuticals Holdings Inc • August 3rd, 2005
WITHPredix Pharmaceuticals Holdings Inc • September 30th, 2005 • Pharmaceutical preparations
October 21, 2002] Ms. Christine Wang [ADDRESS] Re: Employment Agreement Dear Christine, This letter is to confirm our understanding with respect to your future employment by Predix Pharmaceuticals, Inc. or its parent, subsidiaries or affiliates (the...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Massachusetts
PREDIX PHARMACEUTICALS LOGO] 10 K GILL STREET Woburn, MA 01801 Telephone: 781-376-0821Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Massachusetts
Page No. -------- 1. Authorization; Sale of Shares............................................... 1 1.1 Authorization...................................................... 1 1.2 Sale of Securities................................................. 1 1.3...Convertible Preferred Stock Agreement of Sale • August 3rd, 2005 • Predix Pharmaceuticals Holdings Inc • Delaware
February 3, 2005 Kim Drapkin [ADDRESS] Telephone: [TELEPHONE] Re: Employment Agreement Dear Kim: This letter is to confirm our understanding with respect to your future employment by Predix Pharmaceutical Holdings Inc. or its parent, subsidiaries or...Predix Pharmaceuticals Holdings Inc • August 3rd, 2005 • Massachusetts
