Xxxxxxxxx’x Disease. The occurrence of Xxxxxxxxx’x Disease where there is an associated Neurological Deficit that results in Permanent Inability to perform independently atleast three of the activities of daily living as defined below
Xxxxxxxxx’x Disease. The unequivocal diagnosis of idiopathic Xxxxxxxxx’x Disease by a consultant neurologist. This diagnosis must be supported by all of the following conditions: • The disease cannot be controlled with medication; • Signs of progressive impairment; and • Inability of the Life Assured to perform (whether aided or unaided) at least 3 of the following 6 “Activities of Daily Living” for a continuous period of at least 6 months: Activities of Daily Living:
Xxxxxxxxx’x Disease. The unequivocal diagnosis of progressive, degenerative idiopathic Xxxxxxxxx’x disease by a Neurologist acceptable to us. The diagnosis must be supported by all of the following conditions:
Xxxxxxxxx’x Disease. The unequivocal diagnosis of progressive degenerative primary idiopathic Xxxxxxxxx’x disease (all other forms of Parkinsonism are excluded) made by a consultant neurologist. This diagnosis must be supported by all of the following conditions: The disease cannot be controlled with medication; and Objective signs of progressive impairment; and There is an inability of the Life assured to perform (whether aided or unaided) at least 3 of the following five (6) “Activities of Daily Living” for a continuous period of at least 6months. The Activities of Daily Living are:
Xxxxxxxxx’x Disease. The unequivocal diagnosis of progressive, degenerative idiopathic Xxxxxxxxx’x disease before age 60 years, must be supported by the clinical confirmation of a Neurologist. The diagnosis must be supported by all of the following conditions: • the disease cannot be controlled with medication; • signs of progressive impairment; and • inability of the Insured Person to perform at least 3 of the 6 activities of daily living as listed below (either with or without the use of mechanical equipment, special devices or other aids and adaptations in use for disabled persons) for a continuous period of at least 6 months: Activities of daily living:
Xxxxxxxxx’x Disease. Unequivocal diagnosis of idiopathic or primary Xxxxxxxxx’x disease before the age of sixty-five (65), which must be confirmed by a medical specialist. The disease must give rise to a permanent incapacity of performing independently three (3) or more everyday tasks - bathing (being able to take an immersion or shower bath without the assistance of third parties), dressing (being able to dress and undress usual clothes, including any prostheses or orthoses, without the assistance of third parties), personal hygiene (being able to use the bathroom sink and to maintain a reasonable level of hygiene, such as dental hygiene, grooming, shaving and cleaning the excretory organs without the assistance of third parties), mobility (being able to move around the place of residence, on level surfaces, without the assistance of third parties), continence (being able to control the functioning of the intestines and/or bladder (being unable to control one of these functions implying the regular use of diapers or other kind of absorbent shall be considered as incontinence)), eating/drinking (the need to ingest solid and liquid food, prepared and served, necessary for nourishment, including being able to drink through a straw or using other adapted utensils, without the assistance of third parties), or result in being permanently bedridden and unable to get up without external assistance. This condition must be clinically documented for a period of at least three (3) months. Exclusions: - All other types of Parkinsonism that are not idiopathic or primary.
Xxxxxxxxx’x Disease. It was estimated that worldwide from 7 to 10 millions of people are living with Xxxxxxxxx’x Disease (PD) (PD website, 2012). This number is forecast to double by 2030 (EPDA, 2012) and anyway it does not reflect the thousands of cases that often are undetected. The cardinal clinical symptoms are: tremor, postural instability, bradykinesia- hypokinesia, muscular rigidity (Fig. 8). These symptoms lead to walk with difficulties or complications as festination (rapid small steps taken in an attempt to keep the Centre Of Gravity (COG) above the feet while the trunk leans forward involuntarily and shifts the COG forward) and freezing of gait (motor blocks in gait especially at the starting, changing direction or moving in thin places). Thus these motor symptoms are very disabling for patients with PD and undermine the subjects’ autonomy and independence. In PD latency between the beginning of the neurodegenerative process and the appearance of the typical motor symptoms of the disease that lead the clinician to the diagnosis is about 5 years (Xxxxxxxx X.X. et al., 1991; Xxxxxxx X.X. et al., 1998; Xxxxx X. et al., 2001), so the diagnosis is actually expressed when various cerebral areas are already involved in the neuropathological process.
Xxxxxxxxx’x Disease. (PD) Xxxxxxxxx’x disease (PD) was first described in 1817 in ‘An assay on the shaking palsy’ written by the English doctor Xxxxx Xxxxxxxxx (Xxxxxxxxx, 1817). Today, it is the second most common age-related neurodegenerative disorder following AD. It is estimated to affect 1% of the population aged over 60, equivalent to approximately 127,000 individuals in the UK, and up to 5% of the population aged over 85 (xx Xxx and Xxxxxxxx, 2006; Xxxxx et al., 2014). Whilst the vast majority of PD cases are sporadic and idiopathic, 5% of all cases are familial early-onset, with symptoms presenting prior to the age of 60. Such cases can be due to autosomal dominant or recessive mutations, affecting mostly protein metabolism or mitochondrial function (Xxxxx et al., 2014).