Common use of Submitting Investigator Clause in Contracts

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000234 : Group Health/UW Aging and Dementia eMERGE Study Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. IC Specific Access Term : none Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health Research - Marshfield Clinic Consent Group # : 1 Abbreviation : HR_MC Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U Consent Group # : 2 Abbreviation : HR_VU Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. Name : Health Research - Group Health Seattle Consent Group # : 3 Abbreviation : HR_GHS research. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related Name : Dementia or Aging - Group Health Seattle Consent Group # : 4 Abbreviation : AGING_GHS Limited to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health Research - Mayo Clinic Consent Group # : 5 Abbreviation : HR_MYO Mayo Clinic Data may only be used for genetic studies to learn about, prevent, or treat health problems.

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000234 phs000360 : Group Health/UW Aging and Dementia eMERGE Study eMERGE-I Genome Wide Association Studies of Network Phenotypes Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. IC Specific Access Term : none Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health Research - Marshfield Clinic Health/Medical/Biomedical Consent Group # : 1 Abbreviation : HR_MC Data HMB Use Limitation : May be used for genetic studies of this data is limited to learn abouthealth/medical/biomedical purposes, prevent, does not include the study of population origins or treat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U Consent Group # : 2 Abbreviation : HR_VU Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. Name : Health Research - Group Health Seattle Consent Group # : 3 Abbreviation : HR_GHS researchancestry. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related research. Name : Dementia or Aging - Group Health Seattle Disease-Specific (Dementia) Consent Group # : 4 2 Abbreviation : AGING_GHS Limited DS-DEM Use of the data must be related to Dementia. Use of the data must be related to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or Data Use Limitation : other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health Research Health/Medical/Biomedical - Mayo Clinic Genetic Studies Only-No Insurance Companies Consent Group # : 5 3 Abbreviation : HR_MYO Mayo Clinic HM-B-GSO-NIC Data may only be used for Use Limitation : Use of this data is limited to health/medical/biomedical purposes, does not include the study of population origins or ancestry. Use of the data is limited to genetic studies only. No permitted use: Insurance Companies Name : Health/Medical/Biomedical (GSO) Consent Group # : 4 Abbreviation : HMB-GSO Use of this data is limited to learn abouthealth/medical/biomedical purposes, prevent, does not include the study of population origins or treat health problemsancestry. Data Use Limitation : Use of the data is limited to genetic studies only.

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000234 phs000297 : Group Health/UW Aging and Dementia eMERGE Study Resistant Hypertension Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute Important Contacts : xxxxxxxx@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. IC Specific Access Term : none Acknowledgement Statement : Sample statements for the acknowledgment of the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysis. Name : Health Research - Marshfield Clinic Consent Group # : 1 Abbreviation : HR_MC Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U Consent Group # : 2 Abbreviation : HR_VU Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. Name : Health Research - Group Health Seattle Consent Group # : 3 1 Abbreviation : HR_GHS research. Data Use Limitation : These data will be used only for health related research, including research to improve methods for health related Name : Dementia or Aging - Group Health Seattle Consent Group # : 4 2 Abbreviation : AGING_GHS Limited to health research on dementia or other adult conditions related to the aging process. This includes research to improve methods for conducting research that could be applied to dementia or other adult conditions related to the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health Research - Marshfield Clinic Consent Group # : 3 Abbreviation : HR_MC Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U Consent Group # : 4 Abbreviation : HR_VU Data Use Limitation : May be used for genetic studies to learn about, prevent, or treat health problems. Name : Health Research - Mayo Clinic Consent Group # : 5 Abbreviation : HR_MYO Mayo Clinic Data may only be used for genetic studies to learn about, prevent, or treat health problems.. Data Use Limitation : Investigators must state in the Data Use Request their intention to publish or otherwise broadly share any findings from his or her study with the scientific community. Name : Health Research - Northwestern U Consent Group # : 6 Abbreviation : HR_NWU May be used for genetic studies to learn about, prevent, or treat health problems Data Use Limitation :

Submitting Investigator. An investigator who submitted a genomic dataset to an NIH designated data repository (e.g., dbGaP). Study specific DUC addendum phs000234 Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular phs001336 : Group Health/UW Aging and Dementia eMERGE Study Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis Public Posting of Genomic Summary Results - Allowed. NIH Data Access Committee (DAC) : National Human Genome Research Institute NICHD-DAC Important Contacts : xxxxxxxx@xxxx.xxx.xxxXX-XXX@xxxx.xxx.xxx; XXX@xxxx.xxx.xxx In the event of a data management incident, within 24 hours, please contact emails above. Before data dissemination, all requestors must provide a local Institutional Review Board (IRB) letter from their respective institutions approving conduct of the proposed research project and to ensure that anonymity and other provisions are adequately guaranteed. The IRB letter must explicitly reference use of the "Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis" dataset. The requestor of this dataset must also provide a letter of collaboration with Xx. Xxxxxx. Use of these data are limited to health/medical/biomedical purposes. Consequently, studies on population origins or ancestry are not allowed. IC Specific Access Term : none Requestor agrees to make results of studies using the data available to the larger scientific community, either through publication or oral presentations. Use of the data includes methods development research (e.g., development of software or algorithms) as it applies to genetic studies. This dataset is limited to genetic studies only. Use of these data to conduct non-genetic research is prohibited. The annual progress report should cite work done that relates specifically to the “Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis" dataset and not just a generic report for a series of datasets that may also have been requested at the same time. The dataset used for the analyses described in this manuscript were obtained from the database of Genotype and Phenotype (dbGaP) found at xxxx://xxx.xxxx.xxx.xxx.xxx/gap [Accession Number phsxxxxxx]. Samples and associated data for this study ["Extracorporeal Life Support Survival in a Pediatric Hematopoietic Cellular Acknowledgement Statement : Sample statements for Transplant Recipient with Presumed Graft Versus Host Disease-Related Fulminant Myocarditis”] were provided by Xxxxxxx Xxxxxx, M.D., whose project was supported by grants from the acknowledgment Xxxxxx Xxxxxxx Xxxxxxx National Institute of Child Health and Human Development [K12 HD000850], the eMERGE GWAS dataset(s) can be found at the following link: eMERGE dbGaP Acknowledgment Statements (xxxx://xxx.xxxx.xxx.xxx.xxx/projects/gap/cgi-bin/GetPdf.cgi?document_name=eMERGE_Acknowledgement.pdf). Please include all Acknowledgment Statements relevant to the dataset(s) used in your analysisPediatric Blood and Marrow Transplant Foundation, and a National Marrow Donor Program Xxx Xxxxxxxx Xxxxxxxxx Xxxxx. Name : Health Research - Marshfield Clinic Consent Group # : 1 Abbreviation : HR_MC Data Use Limitation : May be used for genetic studies to learn aboutHealth/Medical/Biomedical (IRB, preventPUB, or treat health problems. No Permitted Use: Insurance companies Name : Health Research - Vanderbilt U COL, MDS, GSO) Consent Group # : 2 Abbreviation : HR_VU Data HMB-IRB-PUB-COL-MDS-GSO Use Limitation : May be used for genetic studies of this data is limited to learn abouthealth/medical/biomedical purposes, prevent, does not include the study of population origins or treat health problemsancestry. Name : Health Research - Group Health Seattle Consent Group # : 3 Abbreviation : HR_GHS researchRequestor must provide documentation of local IRB approval. Data Use Limitation : These Requestor agrees to make results of studies using the data will be used only for health related research, including research to improve methods for health related Name : Dementia or Aging - Group Health Seattle Consent Group # : 4 Abbreviation : AGING_GHS Limited to health research on dementia or other adult conditions related available to the aging processlarger scientific community. This includes research to improve methods for conducting research that could be applied to dementia or other adult conditions related to Requestor must provide a letter of collaboration with the aging process. For example, studies of conditions like cataract, diabetes, and psoriasis might be Data Use Limitation : appropriate, while conditions like attention deficit hyperactivity disorder (ADHD) and neuroblastoma might not be appropriate. Studies of conditions that are common in both children and the elderly, such as schizophrenia or depression, would not be appropriate if they focused on children or young adults. Studies focused primarily on pediatric populations are not permitted. Name : Health Research - Mayo Clinic Consent Group # : 5 Abbreviation : HR_MYO Mayo Clinic Data may only be used for genetic studies to learn about, prevent, or treat health problemsprimary study investigator(s).