OECD Principles Clause Samples

OECD Principles. Validation services, even when running against confidential data, should satisfy the 5 OECD principles for (Q)SAR validation. In particular, OpenTox validation web services comply with OECD principles 3 and 4, even when confidential data are involved and A&A services are activated: PRINCIPLE 3: "DEFINED APPLICABILITY DOMAIN" OpenTox provides tools for the determination of applicability domains during the validation of (Q)SAR models against confidential datasets. PRINCIPLE 4: "APPROPRIATE MEASURES OF GOODNESS-OF-FIT, ROBUSTENESS AND PREDICTIVITY" OpenTox provides scientifically sound validation routines for the determination of these measures.