{"component": "clause", "props": {"groups": [{"samples": [{"hash": "toyNMkJhal", "uri": "/contracts/toyNMkJhal#initial-development-plan", "label": "License and Collaboration Agreement (Alnylam Pharmaceuticals, Inc.)", "score": 34.1444206238, "published": true}, {"hash": "h4IzP3EHexR", "uri": "/contracts/h4IzP3EHexR#initial-development-plan", "label": "License and Collaboration Agreement (Alnylam Pharmaceuticals, Inc.)", "score": 24.5646820068, "published": true}, {"hash": "iIQg2ToI693", "uri": "/contracts/iIQg2ToI693#initial-development-plan", "label": "License and Collaboration Agreement (Alnylam Pharmaceuticals, Inc.)", "score": 24.3456535339, "published": true}], "snippet_links": [{"key": "responsible-for", "type": "clause", "offset": [17, 32]}, {"key": "development-of-licensed-products", "type": "clause", "offset": [44, 76]}, {"key": "development-activities", "type": "definition", "offset": [85, 107]}, {"key": "phase-i-completion", "type": "definition", "offset": [137, 155]}, {"key": "all-costs", "type": "definition", "offset": [265, 274]}, {"key": "the-development", "type": "clause", "offset": [279, 294]}, {"key": "by-alnylam", "type": "clause", "offset": [325, 335]}, {"key": "in-the-territory", "type": "clause", "offset": [361, 377]}, {"key": "pursuant-to-the", "type": "clause", "offset": [378, 393]}, {"key": "prior-to-the", "type": "clause", "offset": [464, 476]}, {"key": "milestone-payment", "type": "clause", "offset": [503, 520]}, {"key": "upon-receipt", "type": "clause", "offset": [566, 578]}, {"key": "the-relevant", "type": "clause", "offset": [664, 676]}, {"key": "development-costs-cap", "type": "definition", "offset": [678, 699]}, {"key": "for-development", "type": "clause", "offset": [762, 777]}, {"key": "to-the-extent", "type": "clause", "offset": [875, 888]}, {"key": "excess-costs", "type": "clause", "offset": [894, 906]}, {"key": "to-development", "type": "clause", "offset": [968, 982]}, {"key": "applicable-development", "type": "definition", "offset": [1125, 1147]}, {"key": "approved-by", "type": "definition", "offset": [1171, 1182]}, {"key": "extra-early-development-costs", "type": "definition", "offset": [1197, 1226]}, {"key": "this-exhibit", "type": "definition", "offset": [1263, 1275]}, {"key": "replaced-with", "type": "clause", "offset": [1293, 1306]}, {"key": "the-secretary", "type": "clause", "offset": [1382, 1395]}, {"key": "the-securities-and-exchange-commission", "type": "clause", "offset": [1399, 1437]}, {"key": "confidential-treatment", "type": "definition", "offset": [1476, 1498]}, {"key": "under-rule", "type": "clause", "offset": [1499, 1509]}, {"key": "securities-exchange-act-of-1934", "type": "definition", "offset": [1523, 1554]}], "snippet": "Alnylam shall be responsible for the global Development of Licensed Products and all Development activities with respect thereto through Phase I Completion as set forth in the Initial Development Plan. Alnylam shall be responsible for one hundred percent (100%) of all Costs for the Development activities that are conducted by Alnylam for the Licensed Product in the Territory pursuant to the Initial Development Plan up to a total of (a) [***] dollars ($[***]), prior to the receipt by Alnylam of the Milestone Payment in Section 7.2(a)(i), or (b) [***] ($[***]), upon receipt by Alnylam of the Milestone Payment in Section 7.2(a)(i) (such amount in (a) or (b), the relevant \u201cDevelopment Costs Cap\u201d); provided, however, that, Alnylam shall also bear any Costs for Development activities conducted by Alnylam pursuant to the Initial Development Plan that exceed such amount to the extent such excess Costs [***]. MedCo shall be responsible for all Costs with respect to Development activities for the Licensed Product pursuant to the Initial Development Plan that (a) are conducted by Alnylam, (b) are in excess of the then-applicable Development Costs Cap, and (c) are approved by the JSC (the \u201cExtra Early Development Costs\u201d). CERTAIN CONFIDENTIAL PORTIONS OF THIS EXHIBIT WERE OMITTED AND REPLACED WITH \u201c[***]\u201d. 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"offset": [367, 382]}, {"key": "astellas-eu-agreement", "type": "definition", "offset": [522, 543]}, {"key": "transatlantic-clinical-development-plan", "type": "definition", "offset": [550, 589]}, {"key": "the-jdc", "type": "clause", "offset": [646, 653]}, {"key": "changes-to-the", "type": "clause", "offset": [692, 706]}, {"key": "additional-phase", "type": "definition", "offset": [769, 785]}, {"key": "the-parties", "type": "clause", "offset": [807, 818]}, {"key": "agreed-to", "type": "definition", "offset": [824, 833]}, {"key": "in-addition-to", "type": "clause", "offset": [848, 862]}, {"key": "within-thirty", "type": "clause", "offset": [902, 915]}, {"key": "after-the-effective-date", "type": "clause", "offset": [926, 950]}], "snippet": "The initial Development Plan, along with the associated Development Budget, describing (among other things) the planned development of the Product for the CKD Indications for the U.S., is attached hereto as Exhibit H (the \u201cInitial Development 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The Initial Development Plan includes and shall be integrated with those Phase 3 Clinical Trials that are currently being conducted by FibroGen or Astellas under the U.S. and EU plan for conducting Phase 3 Clinical Trials of the Product for the CKD Indications under the Astellas EU Agreement (the \u201cTransatlantic Clinical Development Plan\u201d or the \u201cTCDP\u201d). FibroGen shall notify AstraZeneca, via the JDC, of all material updates and material changes to the TCDP. The Initial Development Plan shall further outline such additional Phase 3 Clinical Trials as the Parties have agreed to conduct (i.e. in addition to those being conducted under the TCDP). Within thirty (30) days after the Effective Date, the JPT will initiate implementation of the Initial Development Plan.", "size": 4, "hash": "8e05f98d83b38bade472b2f9c8c32d13", "id": 7}, {"samples": [{"hash": "dv1QK7B0aWi", "uri": "/contracts/dv1QK7B0aWi#initial-development-plan", "label": "Collaboration and License Agreement (Facet Biotech Corp)", "score": 21.2847366333, "published": true}, {"hash": "dFAuIortDj4", "uri": "/contracts/dFAuIortDj4#initial-development-plan", "label": "Collaboration and License Agreement (Trubion Pharmaceuticals, Inc)", "score": 21.2108154297, "published": true}, {"hash": "6iuIA2dbSQg", "uri": "/contracts/6iuIA2dbSQg#initial-development-plan", "label": "Collaboration and License Agreement (Facet Biotech Corp)", "score": 21.0, "published": true}], "snippet_links": [{"key": "initial-development-budget", "type": "definition", "offset": [66, 92]}, {"key": "exhibit-b", "type": "definition", "offset": [128, 137]}, {"key": "the-parties-shall", "type": "clause", "offset": [172, 189]}, {"key": "good-faith-efforts", "type": "definition", "offset": [195, 213]}, {"key": "approved-by", "type": "definition", "offset": [294, 305]}, {"key": "signing-date", "type": "clause", "offset": [337, 349]}], "snippet": "A draft of the initial Development Plan, together with associated initial Development Budget, for TRU-016 is attached hereto as Exhibit B (the \u201cInitial Development Plan\u201d). The Parties shall make good faith efforts to agree upon the definitive Initial Development Plan and have it appropriately approved by the JSC within [ * ] after the Signing Date.", "size": 4, "hash": "73bd1215761fa76a35ef81cf52b90778", "id": 8}, {"samples": [{"hash": "gGDkDgcq3OF", "uri": "/contracts/gGDkDgcq3OF#initial-development-plan", "label": "Development, Commercialization and Supply Agreement (Auxilium Pharmaceuticals Inc)", "score": 22.1608486176, "published": true}, {"hash": "begP3RDUyZy", "uri": "/contracts/begP3RDUyZy#initial-development-plan", "label": "Development, Commercialization and Supply Agreement (Auxilium Pharmaceuticals Inc)", "score": 21.0, "published": true}], "snippet_links": [{"key": "the-product", "type": "clause", "offset": [33, 44]}, {"key": "by-the-parties", "type": "clause", "offset": [63, 77]}, {"key": "following-the", "type": "definition", "offset": [78, 91]}, {"key": "applicable-regulatory-authorities", "type": "definition", "offset": [123, 156]}, {"key": "the-eu", "type": "clause", "offset": [160, 166]}, {"key": "pursuant-to-section", "type": "clause", "offset": [167, 186]}, {"key": "to-the-extent", "type": "clause", "offset": [197, 210]}, {"key": "national-meetings", "type": "clause", "offset": [224, 241]}, {"key": "within-the-territory", "type": "definition", "offset": [310, 330]}, {"key": "with-respect-to", "type": "clause", "offset": [348, 363]}, {"key": "risk-management-plan", "type": "clause", "offset": [368, 388]}, {"key": "development-activities", "type": "definition", "offset": [392, 414]}, {"key": "the-parties-shall", "type": "clause", "offset": [445, 462]}, {"key": "the-development-plan", "type": "clause", "offset": [511, 531]}], "snippet": "The initial Development Plan for the Product shall be prepared by the Parties following the Parties\u2019 consultation with the applicable Regulatory Authorities in the EU pursuant to Section 5.2.1(b). To the extent that future \u201cnational meetings\u201d with the Regulatory Authorities in a specific country or territory within the Territory provide guidance with respect to the risk management plan or Development Activities in such country or territory, the Parties shall consider such guidance in updating and amending the Development Plan pursuant to Section 4.3.3.", "size": 4, "hash": "394643d21e3fdc755dcc56c1716ae151", "id": 9}, {"samples": [{"hash": "i8q1DLDEQRR", "uri": "/contracts/i8q1DLDEQRR#initial-development-plan", "label": "Gathering and Compression Agreement (Antero Midstream Corp)", "score": 31.1136207581, "published": true}, {"hash": "1QVpegSRJcL", "uri": "/contracts/1QVpegSRJcL#initial-development-plan", "label": "Gathering and Compression Agreement (ANTERO RESOURCES Corp)", "score": 31.1136207581, "published": true}], "snippet_links": [{"key": "the-development-plan", "type": "clause", "offset": [0, 20]}, {"key": "attached-hereto-as-exhibit", "type": "definition", "offset": [21, 47]}, {"key": "lowest-priority", "type": "clause", "offset": [109, 124]}, {"key": "gathering-system", "type": "definition", "offset": [132, 148]}, {"key": "with-respect-to", "type": "clause", "offset": [149, 164]}, {"key": "capacity-allocations", "type": "clause", "offset": [165, 185]}, {"key": "in-the-event-of", "type": "clause", "offset": [307, 322]}, {"key": "gathering-fee", "type": "clause", "offset": [363, 376]}, {"key": "defined-in-section", "type": "clause", "offset": [381, 399]}], "snippet": "The Development Plan attached hereto as Exhibit D. 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