Common use of Figure Clause in Contracts

Figure. 3 Growth of yeast cells expressing the wild-type adenosine A2B receptor or the N43S mutant receptor. Growth was measured in the absence (control) or presence of 10 µM NECA or 10 µM ZM241385. Each experiment was repeated 3 times, of which the means SEM are shown. *** p 0.001, student’s unpaired t test. Matlab was used to mimic the activation and inhibition of receptors with a high level of constitutive activity (L 1000). The a values were set from 100 for an agonist to 0.1 and 0.01 for inverse agonists. As shown in figure 4, it is hard to detect agonism and inverse agonism of a ligand on receptors with such a big L value. In other words, this receptor is locked in an active state and can not be further activated or inhibited.