Antigens Sample Clauses

Antigens. As of the Effective Date, GNE has already exercised licenses with respect to the following Antigens: HER-2, CD11a, VEGF, and IgE. GNE’s right to elect to obtain any additional licenses shall expire on December 31, 2014.
AutoNDA by SimpleDocs
Antigens. In the event that a Party lists an Antigen in an Antigen List, an In-House List, or, in the case of Medarex, the Medarex Internal Project List, the listing Party shall comply with the following listing requirements, as applicable:
Antigens. All antigens were expressed as recombinant proteins in Pichia pastoris systems and details of gene expression and protein production have already been described elsewhere [33,35,38]. Natural PfAMA1 alleles comprise the full length ectodomain (25-545) of the CAMP [GenBank:M58545], 3D7 [GenBank:U65407), HB3 [GenBank:U33277] and FVO (GenBank:AJ277646] strains of P. falciparum. DiCo proteins consist of amino acids 97 - 545 of the AMA1 ectodomain (domains I, II and III, without the signal sequence). The PfAMA1-MSP119 fusion protein (designated AM) consists of amino acids 106 - 442 (domains I and II) of the FVO AMA1 ectodomain fused with a mutant form of PfMSP119 (amino acids 1526 – 1621) of the Wellcome strain of P. falciparum [35]. All antigens were recognized by the reduction-sensitive rat monoclonal 4G2 antibody suggesting a correct folding of proteins. All antigens were devoid of N-glycosylation sites and the molecular size of the fusion protein product is comparable to that of any of the AMA1 proteins. Animal welfare and ethical clearance Animals used in this study were captive-bred for research purposes. Experimentation and housing were at the Biomedical Primate Research Centre (BPRC) animal facility in Rijswijk, the Netherlands, in accordance with Dutch laws and European Acts (directive 86/609/EEC) on animal experimentation. The BPRC is compliant with recommendations of the Weatherall report on the use of non-human primates in research [39]. The study was approved by an independent ethics committee at BPRC, constituted in accordance with Dutch law on animal experimentation. To minimize discomfort to animals, immunisation and blood sampling were all done under ketamine sedation. The study involved three experimental groups, each with six rhesus monkeys. Animals were assigned in a manner that ensured that age, weight and sex were similar amongst groups, and treatments were randomly assigned to groups. Vaccine formulation, immunisation and bleeding Two of the three groups of rhesus macaques were immunised with DiCo mix in either Montanide ISA 51 (Seppic, Paris, France) or CoVaccine HT™ (Protherics Medicines Development Limited, A BTG International Group Company, London, UK) as adjuvant, and the third group was immunised with the AM fusion protein formulated in Montanide ISA 51. Formulations were made under sterile conditions according to the respective adjuvant manufacturers’ protocols. For Montanide ISA 51 formulations, 276 µl of antigen solution (130 µg/m...
Antigens. As of the Effective Date, GNE has already exercised licenses with respect to the following Antigens: […].

Related to Antigens

  • Human Leukocyte Antigen Testing This plan covers human leukocyte antigen testing for A, B, and DR antigens once per member per lifetime to establish a member’s bone marrow transplantation donor suitability in accordance with R.I. General Law §27-20-36. The testing must be performed in a facility that is: • accredited by the American Association of Blood Banks or its successors; and • licensed under the Clinical Laboratory Improvement Act as it may be amended from time to time. At the time of testing, the person being tested must complete and sign an informed consent form that also authorizes the results of the test to be used for participation in the National Marrow Donor program.

  • Hepatitis B Vaccine Where the Hospital identifies high risk areas where employees are exposed to Hepatitis B, the Hospital will provide, at no cost to the employees, a Hepatitis B vaccine.

  • Influenza Vaccine Upon recommendation of the Medical Officer of Health, all employees shall be required, on an annual basis to be vaccinated and or to take antiviral medication for influenza. If the costs of such medication are not covered by some other sources, the Employer will pay the cost for such medication. If the employee fails to take the required medication, she may be placed on an unpaid leave of absence during any influenza outbreak in the home until such time as the employee has been cleared by the public health or the Employer to return to the work environment. The only exception to this would be employees for whom taking the medication will result in the employee being physically ill to the extent that she cannot attend work. Upon written direction from the employee’s physician of such medical condition in consultation with the Employer’s physician, (if requested), the employee will be permitted to access their sick bank, if any, during any outbreak period. If there is a dispute between the physicians, the employee will be placed on unpaid leave. If the employee gets sick as a reaction to the drug and applies for WSIB the Employer will not oppose the application. If an employee is pregnant and her physician believes the pregnancy could be in jeopardy as a result of the influenza inoculation and/or the antiviral medication she shall be eligible for sick leave in circumstances where she is not allowed to attend at work as a result of an outbreak. This clause shall be interpreted in a manner consistent with the Ontario Human Rights Code.

  • Research Collaboration Upon FibroGen’s request, the Parties will discuss conducting a research program funded by AstraZeneca and directed toward franchise enhancement and lifecycle management for HIF Compounds or other topics that the Parties determine relevant to the Products and the Field. Upon agreement on the terms of such research program, the Parties will enter into a separate agreement or amend this Agreement accordingly.

  • Collaboration We believe joint effort toward common goals achieves trust and produces greater impact for L.A. County’s youngest children and their families.

  • Research Plan The Parties recognize that the Research Plan describes the collaborative research and development activities they will undertake and that interim research goals set forth in the Research Plan are good faith guidelines. Should events occur that require modification of these goals, then by mutual agreement the Parties can modify them through an amendment, according to Paragraph 13.6.

  • Preceptor A per diem Registered Nurse 2 may serve as a preceptor after successfully completing a preceptor workshop or equivalent documented training and agreeing to and being appointed to be specifically responsible for planning, organizing, and evaluating the new skill development of one or more RNs as appropriate enrolled in a defined orientation program, the parameters of which have been set forth in writing by the Employer. This includes teaching, clinical supervision, role modeling, feedback, evaluation (verbal and written) and follow up of the new or transferring employee. The per diem RN 2 preceptor is eligible to receive preceptor premium pay when actually engaged in preceptor role responsibilities with/on behalf of the orienting RN. A per diem RN 2 substituting for the original preceptor during a period of absence and who has been designated to carry out the preceptor's complete responsibility (including following and/or adjusting the plan to meet learning needs and providing oral and written evaluation input) will receive preceptor pay. A preceptor may be assigned to a student when it is determined by the Employer that the employee has completed the required preceptor training or has agreed to and been appointed a preceptor. The employee is specifically responsible for planning, organizing, and evaluating the new skill development of the student as appropriately enrolled in a defined program, the parameters of which have been set forth in writing by the Employer. This includes teaching, clinical supervision, role modeling, feedback, evaluation (verbal and written) and follow up of the student.

  • Research Program 2.1 University will use reasonable efforts to conduct the Research Program described in Attachment A which is hereby incorporated in full by reference (“Research Program”), and will furnish the facilities necessary to carry out said Research Program. The Research Program will be under the direction of _____________________ (“Principal Investigator”), or his or her successor as mutually agreed to by the Parties and will be con­ducted by the Principal Investigator at the University.

  • Library CONTRACTOR shall provide an inmate law library in compliance with Rule 33-501.301, F.A.C., FDC’s Policy 501.301, and ACA Standards.

  • Background Screening VENDOR shall comply with all requirements of Sections 1012.32 and 1012.465, Florida Statutes, and all of its personnel who (1) are to be permitted access to school grounds when students are present, (2) will have direct contact with students, or (3) have access or control of school funds, will successfully complete the background screening required by the referenced statutes and meet the standards established by the statutes. This background screening will be conducted by SBBC in advance of VENDOR or its personnel providing any services under the conditions described in the previous sentence. VENDOR shall bear the cost of acquiring the background screening required by Section 1012.32, Florida Statutes, and any fee imposed by the Florida Department of Law Enforcement to maintain the fingerprints provided with respect to VENDOR and its personnel. The parties agree that the failure of VENDOR to perform any of the duties described in this section shall constitute a material breach of this Agreement entitling SBBC to terminate immediately with no further responsibilities or duties to perform under this Agreement. VENDOR agrees to indemnify and hold harmless SBBC, its officers and employees from any liability in the form of physical or mental injury, death or property damage resulting from VENDOR’s failure to comply with the requirements of this section or with Sections 1012.32 and 1012.465, Florida Statutes.

Time is Money Join Law Insider Premium to draft better contracts faster.