Acute Toxicity Sample Clauses

Acute Toxicity. ‌ 4 Studies on the acute toxicity of technical grade indaziflam in fish were submitted to U.S. EPA in 5 support of the registration of indaziflam and are summarized below and in Appendix 6. Acute 6 toxicity studies were conducted in three species of freshwater fish (bluegill sunfish, fathead minnow, 7 and rainbow trout) and in one saltwater species (sheepshead minnow) (U.S. EPA/OPP 2010a). U.S. 8 EPA typically uses 96-hour LC50 values in fish to assess the potential for acute risks in fish. Several of 9 the studies are considered supplemental because centrifugation was not used to measure dissolved 10 test concentrations (MRID 47443233, MRID 47443234, MRID 47743305, and MRID 47443232). 11 The acute toxicity of technical grade indaziflam in freshwater fish was evaluated in three studies. In 12 bluegill sunfish (Lepomis macrochirus), a 96-hour LC50 of 0.32 mg total a.i./L and a NOAEC of 0.21 mg 13 total a.i./L was identified based on lethal and sublethal effects (MRID 47443233). The sublethal 14 effects observed included loss of equilibrium, loss of vertical orientation, labored respiration, and 15 lying on the bottom. A 96-hour LD50 of 0.57 mg total a.i./L was identified in rainbow trout 16 (Oncorhynchus mykiss; MRID 47443234). The NOAEC was based on mortality, at a value of 0.42 mg 17 total a.i./L. Loss of equilibrium was observed at the highest treatment concentration at 4 hours with 18 complete mortality observed at 24 hours. This precluded the ability to observe sublethal effects 19 thereafter. In fathead minnow (Pimephales promelas), a 96-hour LC50 of 0.77 mg total a.i./L and a 20 NOAEC of 0.27 mg total a.i./L was identified for sublethal effects (MRID 47443229). The sublethal 21 effects observed were dose-dependent and included loss of equilibrium and erratic behavior. 22 A study was also submitted on the toxicity of Esplanade 500 SC to bluegill sunfish (MRID 47743305). 23 In this study, a 96-hour LC50 of 0.372 mg total a.i./L and a NOAEC of 0.251 mg total a.i./L was 24 identified based on lethal and sublethal effects. Sublethal effects were dose-dependent and included 25 fish on the bottom of the aquarium, dark coloration, hyperactivity, inactivity, labored respiration, 26 loss of equilibrium with lateral deviation, and/or lying on their sides or backs.
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Related to Acute Toxicity

  • Infectious Diseases The Employer and the Union desire to arrest the spread of infectious diseases in the nursing home. To achieve this objective, the Joint Health and Safety Committee may review and offer input into infection control programs and protocols including surveillance, outbreak control, isolation, precautions, worker education and training, and personal protective equipment. The Employer will provide training and ongoing education in communicable disease recognition, use of personal protective equipment, decontamination of equipment, and disposal of hazardous waste.

  • Diagnosis For a condition to be considered a covered illness or disorder, copies of laboratory tests results, X-rays, or any other report or result of clinical examinations on which the diagnosis was based, are required as part of the positive diagnosis by a physician.

  • Study An application for leave of absence for professional study must be supported by a written statement indicating what study or research is to be undertaken, or, if applicable, what subjects are to be studied and at what institutions.

  • ENDANGERED SPECIES The Endangered Species Act of 1973 (16 U.S.C. § 1531, et seq.) as amended, particularly section 7 (16 U.S.C. § 1536).

  • Human Leukocyte Antigen Testing This plan covers human leukocyte antigen testing for A, B, and DR antigens once per member per lifetime to establish a member’s bone marrow transplantation donor suitability in accordance with R.I. General Law §27-20-36. The testing must be performed in a facility that is: • accredited by the American Association of Blood Banks or its successors; and • licensed under the Clinical Laboratory Improvement Act as it may be amended from time to time. At the time of testing, the person being tested must complete and sign an informed consent form that also authorizes the results of the test to be used for participation in the National Marrow Donor program.

  • Screening 3.13.1 Refuse containers located outside the building shall be fully screened from adjacent properties and from streets by means of opaque fencing or masonry walls with suitable landscaping.

  • Hepatitis B Vaccine Where the Hospital identifies high risk areas where employees are exposed to Hepatitis B, the Hospital will provide, at no cost to the employees, a Hepatitis B vaccine.

  • Health and hygiene The Hirer shall, if preparing, serving or selling food, observe all relevant food health and hygiene legislation and regulations. In particular dairy products, vegetables and meat on the premises must be refrigerated and stored in compliance with the Food Temperature Regulations. The premises are provided with a refrigerator and thermometer.

  • Clinical 2.1 Provides comprehensive evidence based nursing care to patients including assessment, intervention and evaluation.

  • Accident Prevention Health and Safety Committee The Employer and the Union agree that they mutually desire to maintain standards of safety and health in the Hospital in order to prevent accidents, in jury and illness. its responsibilities under the applicable legislation, the agrees to accept as a member of its Accident Prevention Health 6 Safety Committee at l e a s t one representative selected or appointed by the Union from amongst bargaining unit employees. shall identify potential dangers and hazards, institute means of improving health and programs and recommend to be a e improve related and health. The Hospital agrees to co-operate i providing information to enable the Committee to its function. shall i be at the call of Chair if shall minutes O f all meetings t h e s a m e available for representative o r selected accordance with shall serve for a of one calendar year the date of appointment which may renewed for further periods of one year. off for such to attend meetings of the Accident Prevention and Safety Committee accordance with shall and spent s h a l l be deemed to b e work time for which the representative(s) shall be paid by the a t his/her regular or premium rate as m a y be applicable. ARTICLE PAID The Holidays with pay for this Agreement shall be: New's Years Day Good Friday Easter Monday Victoria Day Dominion Da) Holiday (as locally declared) During of this the Day, which is not a day, shall be granted third in If a that shall replace this holiday. t the nature of services necessary a Hospital, of the e m p l o y e e s ma be required work these In general, may required alternate with other in absent instance, an e m p l o y e e having Day off 0 be off on Year's Day. a the preference. To qualify for holiday pay as above, an employee must work his or her full regularly scheduled shift immediately preceding and his or her full regularly scheduled shift immediately succeeding the Holiday. In the event of an employee being prevented from working the shift immediately preceding and/or succeeding such holiday by reason of illness, authenticated by medical certificate or otherwise, lasting more than five full working such employee shall qualify for holiday pay, it being further understood and agreed that no employee shall receive holiday pay for more than one holiday during any one illness except for holidays over the Christmas and Year's periods, in which case no employee shall receive pay for more than three holidays. of the above named holidays an regular day off, or during his or her vacation the employee receive off payment for holidays in lieu thereof, but additional shall not be added to the period of vacation of employee except the of the Department his work shall time half time rate of o r . such in addition any entitled or at the option of the the employee may be paid time one half for the time worked and a paid day off in lieu thereof, or, (or a further option of the Hospital), the employee may be paid his regular straight time plus a paid clay and a half off in lieu thereof. Failure report for work assigned on such holiday shall disqualify employee for holiday pay.

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