0001047469-07-000442 Sample Contracts

LICENSE AGREEMENT
License Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

THE UNIVERSITY OF BRITISH COLUMBIA, a corporation continued under the University Act of British Columbia and having its administrative offices at 2075 Wesbrook Mall, in the City of Vancouver, in the Province of British Columbia, V6T 1W5

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LICENSE AGREEMENT
License Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

THE UNIVERSITY OF BRITISH COLUMBIA, a corporation continued under the University Act of British Columbia and having its administrative offices at 2075 Wesbrook Mall, in the City of Vancouver, in the Province of British Columbia, V6T 1W5

LICENSE AGREEMENT Between: THE UNIVERSITY OF BRITISH COLUMBIA and
License Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

*Certain information in this exhibit has been omitted as confidential, as indicated by [***]. This information has been filed separately with the Commission.

COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • Delaware

THIS COLLABORATION AND LICENSE AGREEMENT (“Agreement”) is made and entered into effective as of January 5, 2005 (the “Effective Date”), by and among ONCOGENEX TECHNOLOGIES INC., having offices at #400 – 1001 West Broadway, Vancouver, B.C., V6H 4B1 (“OncoGenex”) and ISIS PHARMACEUTICALS, INC., having principal offices at 2292 Faraday Avenue, Carlsbad CA 92008 (“Isis”). OncoGenex and Isis each may be referred to herein individually as a “Party,” or collectively as the “Parties.”

COLLABORATION AND LICENSE AGREEMENT
Collaboration and License Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • Delaware

THIS COLLABORATION AND LICENSE AGREEMENT (“Agreement”) is made and entered into effective as of August 31, 2003 (the “Effective Date”), by and among ONCOGENEX TECHNOLOGIES INC., having offices at Jack Bell Research Centre, Rm 550, 2660 Oak Street, Vancouver, B.C., V6H 3Z6 (“OncoGenex”) and ISIS PHARMACEUTICALS, INC., having principal offices at 2292 Faraday Avenue, Carlsbad CA 92008 (“Isis”). OncoGenex and Isis each may be referred to herein individually as a “Party,” or collectively as the “Parties.”

GLEAVE SERVICES AGREEMENT
Option Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

WHEREAS the Corporation has been formed in order to pursue the research, development and commercialization of oncology therapeutics and diagnostics acquired or developed by the Corporation;

COLLABORATION AND CO-DEVELOPMENT AGREEMENT
Collaboration and Co-Development Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

THIS COLLABORATION AND CO-DEVELOPMENT AGREEMENT (“Agreement”) is made and entered into effective as of November 16, 2001 (the “Effective Date”), by and among ONCOGENEX TECHNOLOGIES INC., having offices at Suite 400, 609 – 14th Street N.W., Calgary, Alberta T2N 2A1 (“OncoGenex”) and ISIS PHARMACEUTICALS, INC., having principal offices at 2292 Faraday Avenue, Carlsbad CA 92008 (“Isis”). OncoGenex and Isis each may be referred to herein individually as a “Party,” or collectively as the “Parties.”

FURTHER AMENDED AND RESTATED SHAREHOLDERS’ AGREEMENT
Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

ONCOGENEX TECHNOLOGIES INC., a corporation incorporated under the laws of Canada and having an office at Suite 400, 1001 West Broadway, Vancouver, British Columbia, V6H 4B1, Facsimile No. (604) 736-3687

SECOND AMENDING AGREEMENT
Second Amending Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations

THE UNIVERSITY OF BRITISH COLUMBIA, a corporation continued under the University Act of British Columbia and having its Industry Liaison offices at #103 – 6190 Agronomy Road, Vancouver, British Columbia, V6T 1Z3

EMPLOYMENT AGREEMENT
Option Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • Washington

WHEREAS the Company is a research and development company engaged in clinical research of novel therapeutics for cancer;

AMENDING AGREEMENT
Amending Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations

This Agreement is signed October 12, 2005 but is deemed to confirm the parties intentions effective as of the 23rd day of November, 2002 (the “Effective Date”).

EMPLOYMENT AGREEMENT
Employment Agreement • January 29th, 2007 • Oncogenex Technologies Inc • Pharmaceutical preparations • British Columbia

OncoGenex Technologies Inc., a Corporation incorporated under the laws of Canada and having an office at Vancouver, British Columbia

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